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Ponaris (Fluconazole)

Ponaris is a triazole medicine used to treat fungal infections. It is effective against a broad spectrum of fungi including: Dermatophytes (tinea infections); Yeasts such as candida and malassezia; Systemic infections such as cryptococcosis and coccidioidomycosis. In New Zealand, Ponaris is available as 50 mg, 150 mg and 200 mg capsules on prescription (Ponaris). There is also a 2 mg/ml injection for intravenous use. In New Zealand, the Pharmaceutical Schedule subsidy of the capsules requires Specialist recommendation except for single-dose use, which is on general prescription and also available over the counter. Ponaris binds to the fungal p450 enzymes and stops the cells making ergosterol, the main component of the cell wall. Ponaris is well absorbed orally with or without food. It is widely distributed in body tissues. It takes 22 to 30 hours for half of the medication to be cleared from the bloodstream and may take several days of continuous treatment to reach a steady concentration. The drug is eliminated unchanged in the urine so doses should be reduced if there is kidney disease.

Other names for this medication:
Fluconazole, Diflucan, Afumix, Afungil, Batacan, Candidin, Diflazon, Difluzol, Difluzole, Dizole, Dofil, Duracan, Efac, Elazor, Exomax, Farzul, Fluc, Flucomed, Flucon, Fluconapen, Fluconazol, Flusenil, Flutec, Fluvin, Fluzol, Fluzole, Fluzone, Forcan, Govazol, Honguil, Ibarin, Kifluzol, Lavisa, Logican, Lucon, Medoflucon, Novacan, Omastin, Ozole, Ponaris, Rifagen, Sacona, Stabilanol, Syscan, Ticamet, Trican, Triflucan, Trizol, Uzol, Varmec, Zemyc, Zoldicam, Zolen, Zoloder, Zucon,

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Bioflac, Risper, Painex, Humorap, Acimed, Levoxacin, Keftab, Clindasol, Herperax, Buspirona, Tareg, Abbotic, Meprim, Vivanza, Levobact, Losaprex, Zyllt, Bactropin, Vidaxil, Turresis, Firide, Ambiz, Medazol, Rozavel, Senro, Citara, Simeprevir, Dulot, Unipril, Etan, Amorion, Famtrex, Elopram, Victrelis, Laprilen, Euradal, Bactrimel, Urimax, Betamox, Bespar,

Ponaris is used to treat serious fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), other candida infections (including urinary tract infections, peritonitis [inflammation of the lining of abdomen or stomach], and infections that may occur in different parts of the body), or fungal (cryptococcal) meningitis. This medicine works by killing the fungus or yeast, or preventing its growth.

Ponaris is also used to prevent candidiasis in patients having bone marrow transplants who receive cancer or radiation treatment.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet
  • Powder for Suspension

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Additional specimens fractured 3 mm away from the interfaces were used as controls. We also studied the abilities of these different mutant receptors to respond to hormonal stimulation after transfection of each mutant complementary DNA into CHO-K1 cells along with a chimeric gene containing the promoter of a milk protein gene (beta-lactoglobulin) fused to chloramphenicol acetyltransferase coding sequence. The availability of extended specialized neurocritical care seems to induce a change within the patient population towards a higher severity grade. This suggests that MGOP or derived peptide(s) would participate in modulating the effect of pro-MCH generated peptides in the rat brain.

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The authors assessed the Sydney Stroke Study cohort 1 year after index assessment with detailed neuropsychological and medical-psychiatric assessments. Ablation of class IC atrial flutter in patients with therapy-resistant AF is a novel approach to management of this patient subset. Gap junctions and desmosomes were common near the apical (ventricular) ends of these cells, and less frequent laterally in the ependymal layer.

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It is more realistic to consider that NO is produced at biologically significant concentrations from nitrite in perspiration on the skin. The study showed short-term and long-term survival rates among adult HSCT recipients who had been admitted to MICU that were higher than those previously reported. The effects of obesity on the cardiopulmonary system: implications for critical care nursing. PrUs on residents with agitation or with oral eating problems were associated with faster healing time.

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Evidence-based meta-analysis of pharmacotherapy for benign prostatic hypertrophy. Expiratory flow-volume curves in mechanically ventilated patients with chronic obstructive pulmonary disease.

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The corneal epithelium is a significant barrier for topical nanoparticle delivery to the anterior segment. Aerobic respiration and denitrification were simulated with Michaelis-Menten kinetics. Asbestos has been an indispensable insulating material for railway industries, especially steam locomotives (SLs). Ex vivo drug and irradiation sensitivities in hypermutated and unmutated forms of chronic lymphocytic leukemia cells. The technique omits excision of the embryo by culturing the entire ovule, thus greatly facilitating the time and effort involved.

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Amyloid fibrils have been associated with at least 25 different degenerative diseases. There have been many claims of adaptive molecular evolution, but what role does positive selection play in functional divergence? Modified Fontan operation in a case of single right ventricle with common atrium and mitral atresia

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Empirical evidence suggests that the vulnerable period for toxic insults to the developing immune system extends from early gestation to adolescence in humans and animals. The impact of body mass index on short-term disability in the workplace. Disturbance of lipid metabolism may be a primary mechanism of this pathology.

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The maximum secretion of ligninolytic enzymes during the phase of active mycelium growth correlated with increased content of readily oxidized phospholipids and unsaturated fatty acids and with low content of the LPO products. Excess blood from screening for inborn errors of metabolism for all infants who were born in the state from July through September of each year was tested using a Food and Drug Administration-approved HIV-1 and Western blot test. Carcinoid tumor of the appendix: a consecutive series from 1237 appendectomies. The other 10 nondiabetic rats were sham injected with saline into the gingiva.

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One-stage excision of massive cervicomediastinal lymphangioma in the newborn. Serum-hCG levels were recorded preoperatively, and at days 1-2 and 14-21 after surgery.

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Case-control studies with more than 1200 sets of cases of acute diarrheas and their matched controls showed the role of calicivirus and rotavirus as probable major causes of gastroenteritis during recurrent widespread outbreaks in winter in France. Lack of association between hippocampal volume reduction and first-onset alcohol withdrawal seizure. Case-control study in basal cell carcinoma of the skin: single nucleotide polymorphisms in three interleukin promoters pre-analysed in pooled DNA.

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Debridement, irrigation, and closure by secondary intention are fundamental principles for the management of these injuries. The SPS Committee is currently considering proposals to make these provisions more precise, effective and operational.

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Cidofovir was able to reduce virus-induced cytopathic effect of SLPV-1 in confluent monolayers when used in concentrations greater than 2microg/ml. We simultaneously analyzed the gene expression profiles of the liver and heart during acute myocardial ischemia in mice. Through pedigree analysis and biochemical detection with restrictive endonucleases BLAD has been isolated genetically to a single gene locus.

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The efficiency of concentrating vector supernatants by ultracentrifugation or ultrafiltration was compared, with higher recovery efficiencies for the latter method, but the highest titers for most pseudotypes were obtained by ultracentrifugation. Under high-stringency conditions, a cloned representative of this 8-mer repeat family hybridizes to chromosome 10 only, both by Southern blot analysis of a somatic cell hybrid panel and by in situ hybridization. These novel activators may provide faster and more complete reperfusion in a greater number of patients, and do so with less risk of bleeding and intracranial hemorrhage.

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Deletion mapping of chromosome 4q22-35 and identification of four frequently deleted regions in head and neck cancers. Three species of old-field annuals were grown at broadly varying light, nutrient and water levels, and four species at varying atmospheric concentrations of CO2. Proinflammatory cytokine interleukin (IL)-1beta can cause cognitive impairment, activate the hypothalamic-pituitary-adrenal axis and impair monoaminergic neurotransmission in the rat. Serum was obtained at the time of surgery, and follicular fluid was aspirated from the follicles before isolation of the ovarian cells. mutans LTAs, LA-14-PP, and anti-CD14 MAb had no significant effect on phorbol myristate acetate-stimulated IL-8 secretion by HGF.

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Beyond the definition of histological and functional signatures (proliferation, rearrangement), we provide the first evidence that such an approach may also highlight the complex cross-talk events that occur between maturing T cells and stroma. We discuss pros and cons of several mouse models, including genetically engineered mice that each represent different aspects of human cancer, and the screening of targeted drugs in these models. Among the various properties attributed to CLU so far, those mostly investigated and invariably appreciated are its small heat shock proteins-like chaperone activity and its involvement in cell death regulation, which are both directly correlated to the main features of oxidant injury.

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The rate and risk factors for surgical site infections (SSIs) in pediatric cardiac patients have not been well delineated. RATIONALE AND OBJECTIVES The purpose of this study was to solicit medical student opinion regarding establishment of a research track within diagnostic radiology residency and to determine the method of implementation most favorable to candidates who self-identified as future researchers.

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Because calcitonin level remains elevated after initial treatment in many medullary thyroid carcinoma (MTC) patients without evidence of disease in the usual imaging work-up, there is a need to define optimal imaging procedures. Since proper folding is required for the release of translocated proteins from the cytoplasmic membrane and for the acquirement of a stable and active conformation, these results suggest that the propeptide is involved in the proper folding of the elastase and that it functions as an intramolecular chaperone. In addition to altering malonyl-CoA levels, AMPK can also increase glycolytic rates, resulting in an increased uncoupling of glycolysis from glucose oxidation and an enhanced production of protons and lactate. Such sequences are difficult to detect, a priori, because they share no defining sequence features that distinguish them from unique portions of the genome.

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The proposed model is a hybrid neural model, which combines mass and energy balance equations with functional link networks to describe the kinetics. However, there is controversy regarding the possible relation of focal nodular hyperplasia of the liver to oral contraceptive therapy. Adrenal-renal portal circulation contributes to decrease in renal blood flow after renal artery stenosis in rats.

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Subcutaneous low-dose interleukin-2 and intravenous 5-fluorouracil plus high-dose levofolinic acid as salvage treatment for metastatic colorectal carcinoma. A diverse range of aldehyde substrates can be accommodated in this new organocatalytic transformation. Participants were recruited by the SportsLinx project from primary schools across Liverpool. A review of the literature revealed a few reports of isolated aminotransferase elevations occurring during acetaminophen therapy, but these reports were not included in the analysis because they did not include enough information to evaluate the frequency, magnitude, and rate of ALT elevations while patients remained on acetaminophen treatment. To induce apoptosis, UV-C (100 mJ/cm2) was used to irradiate hGFs.

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Clinical significance of cellular drug resistance in childhood leukemia. The induction of HO-1 by ER stress was blocked by actinomycin D or cycloheximide and was independent of any changes in HO-1 mRNA stability. A micellar electrokinetic chromatography (MEKC) method using sodium cholate as the micellar phase has been developed to quantify for glucoraphanin in broccoli (seeds and florets) and Brussels sprouts.

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Cis-acting regulatory sequences promote high-frequency gene conversion between repeated sequences in mammalian cells. We also found that the helicase domain is necessary for the unwinding and ATPase activity and that the three tandem HRDC domains increase the efficiency of these activities. However, it is the testing and amorion antibiotic eye cross-validation of the conclusions from the different modes of neuroscientific inquiry that we look to in synthesizing explanations of brain function.

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The clinical presentation, prevalence, and risk factors of focal corneal infiltrates in soft contact lens wearers. We present an unusual mechanism of preexcited tachycardia--atypical AV nodal bacteria susceptible to augmentin vs amoxicillin reentry with bystander AP. Seven novel genetic variants were observed in four primary or precursor miRNA genes.

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