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Asthafen (Azelastine)
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Azelastine

Asthafen is an antihistamine administered in aqueous solution as a nasal spray. It exhibits histamine H1 receptor antagonist activity and is used as a racemic mixture. No difference in pharmacologic activity between its enantiomers has been observed. Asthafen HCl is used to treat seasonal allergic rhinitis (e.g., hay fever) and perennial rhinitis (including runny nose, sneezing, and nasal itching). It is also used in eyedrops to treat allergic conjunctivitis. It is considered to be a very safe drug with no serious side effects. Asthafen HCl has been known since 1980, but its first US Food and Drug Administration approval for use as a nasal spray was awarded to Meda Pharmaceuticals (Somerset, NJ) under the brand name Astepro in 2008. Since its first registration, the drug has been sold under many brand names and is now generic.

Other names for this medication:
Azelastine, Afluon, Allergodil, Astelin, Astepro, Asthafen, Azel, Azelastin, Azelastina, Azelone, Azen, Azep, Azeptin, Ketasma, Lastin, Optilast, Optivar, Otrivine, Phenergan, Rhinolast, Rinalin, Xanaes,

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Asthafen nasal spray is used to help relieve symptoms (eg, stuffy or runny nose, itching, sneezing) of seasonal (short-term) or perennial (year-round) allergic rhinitis (hay fever), and vasomotor rhinitis.

Asthafen is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Spray

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Finite Element Simulation Study of a Frontal Driver Airbag Deployment for Out-of-Position Situations. The known fauna of livestock in the Maghreb consists of 5 established species. In 50 patients with FSGS, fractional excretion (FE) of immunoglobulin G (IgG), albumin, transferrin, and alpha(1)-microglobulin (alpha(1)m) was calculated. Ototoxic effects of occupational exposure to styrene and co-exposure to styrene and noise.

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Proliferating cell nuclear antigen (PCNA) is a DNA polymerase cofactor and regulator of replication-linked functions. The aim of this study was to test the influence of training on parameters assessed during conscious mouse echocardiography. Recovery from heart failure: structural and functional analysis in a canine model. Assessment of aluminum production emission induced risk to human health Six PCs with different lengths of acyl hydrocarbon chains and different degrees of unsaturated acyl hydrocarbon chains were selected to examine influences of a lipophillic part of phosphatidylcholines in emulsion and dispersion systems.

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The results were obtained by examining a population of male residents chronically exposed to heavy metals (Pb, Cu) in the environment. However, the precise contribution of periventricular hyperintensities (PVH), deep white matter hyperintensities (DWMH), and medial temporal lobe atrophy (MTA) to task performance remains unspecified. Two acetates were identified as (11Z,13)-tetradecadien-1-yl acetate and (11Z)-tetradecen-1-yl acetate by comparison with synthesized references. The resuscitation fluids, including crystalloids and colloids, were tested in an experimental module with 16-gauge central and peripheral catheters. It was followed by cell death, however, only in the absence of NGF and/or cAMP, and was no longer required for apoptosis in NGF/cAMP-differentiated cells.

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However, the role of H3 N-terminal lysine acetylation and the corresponding lysine acetyltransferase (KAT) in RC nucleosome assembly are not known. Retroreflectance measurements of photometric standards and coatings. These studies show a dual effect of NE on cell mobilization from the spleen: cell retention by decreasing blood flow and stimulation of cell output by a beta-adrenergically mediated, smooth muscle-independent mechanism.

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Several cases of human cyanobacterial poisoning have been documented, but accurate assessment of the risk is difficult for lack of knowledge concerning exposure levels and the incidence of this kind of poisoning. To determine what Spanish primary healthcare physicians consider the rates of pneumococcal resistance to be, the type of antimicrobial treatment they would prescribe on suspicion of high resistance and ascertain in which cases of acute bronchitis these physicians would initiate antibiotic treatment. These subscale representations are calculated using systematic sampling from the corresponding terminal group. Acute training in racing horses at two different levels of effort: A haemorheological analysis. Morphine was administered twice daily increasing the daily dose from 20 to 50 mg/kg during 7 days.

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Relationships between dental and skeletal maturity in Turkish subjects. Whether selective factor IXa inhibition produces an appropriate anticoagulant effect when combined with platelet-directed therapy in patients with stable coronary artery disease is unknown. Clinical outcome of conservative therapy for stage T1, grade 3 transitional cell carcinoma of the bladder. The aim of this study is to provide to indexers MeSH terms to be considered as major ones in a list of terms automatically extracted from a document. Numerical simulations were also performed using a boundary element method.

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Only ICV lesions lead to memory impairments in passive avoidance and Morris water maze tasks. Pulmonary absorption of recombinant human granulocyte colony-stimulating factor (rhG-CSF) after intratracheal administration to rats. Pathological pain is an expression of neural plasticity that occurs both in the peripheral nervous system (e.g., primary sensory nociceptors), termed peripheral sensitization, and in the central nervous system (e.g., dorsal horn and brain neurons), termed central sensitization.

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Reactive oxygen species produced by the knockdown of manganese-superoxide dismutase up-regulate hypoxia-inducible factor-1alpha expression in oral squamous cell carcinoma cells. The failure to observe p107-containing complexes in myotubes appears to be due to the differentiation-specific induction of both p130 and cyclin D3, p107 is found in complexes with cyclin D3 in myotubes, and the addition of exogenous cyclin D3 or p130 to lysates from undifferentiated L6 cells was able to disrupt p107-containing E2F-site binding complexes.

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The addition of a bedtime H2 receptor antagonist (H2RA) to proton pump inhibitor (PPI) b.i.d. Only polygenic mutation-selection balance seems consistent with the data on mental disorder prevalence rates, fitness costs, the likely rarity of susceptibility alleles, and the increased risks of mental disorders with brain trauma, inbreeding, and paternal age.

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A-kinase-anchoring proteins (AKAPs) are a diverse family of about 50 scaffolding proteins. Four of these tumors were diffuse large B-cell lymphomas (DLCLs) with concordant reduced levels of mRNA, whereas one blastoid mantle cell lymphoma (B-MCL) and two DLCLs had relatively normal levels of mRNA. One patient died from metastatic transitional cell cancer 18 months postoperatively whereas one died perioperatively secondary to bleeding and multiple organ failure.Of five patients who tolerated endoscopic therapy, four were disease free with a mean follow-up of 30 months. A new variable pulse-duration PDL improves a refractory port-wine stain.

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