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Avastatin (Atorvastatin)

Simvastatin and Avastatin resulted in smaller increases with age in the weight, concentrations of RNA and protein, and activity of MAP kinase in the left ventricular free wall, whereas pravastatin did not. A double-blind trial on the effects of Avastatin on glycemic control in Japanese diabetic patients with hypercholesterolemia.

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Ezetimibe and Avastatin combination is used together with a proper diet to treat high cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems (eg, heart attack, stroke) caused by clogged blood vessels. It is also used to treat a condition called homozygous familial hypercholesterolemia (HoFH).

Ezetimibe is a cholesterol absorption inhibitor and Avastatin is an HMG-CoA reductase inhibitor, or statin. These medicines will reduce the absorption of cholesterol from foods and the production of cholesterol in your body.

This medicine was available only with your doctor's prescription.

The Avastatin/ezetimibe combination (Liptruzet(R)) was withdrawn from the United States market on June 2, 2015.

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Up-regulation of mitochondrial Bax expression and down-regulation of Bcl-x(L) expression also participated in the apoptosis induced by NCTD. Betaine supplementation decreased homocysteine in all three genotypes, restored liver betaine and phosphocholine pools, and prevented severe steatosis in Mthfr-deficient mice. Strains of Enterococcus faecalis harbouring various copy numbers of the vanRSHAX cluster were tested to determine if there was a correlation between the levels of resistance to glycopeptides, the levels of expression of the corresponding resistance genes and the relative proportions of the different cytoplasmic peptidoglycan precursors. We studied the analgesic effects of 1 g paracetamol given rectally at the end of surgery in a prospective, randomised, double-blind study.

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To develop a combined algorithm of liver stiffness measurement (LSM) and serum test formula to predict advanced liver fibrosis in chronic hepatitis B. The items were grouped as a negative symptom subscale in the CPRS. Increased perfusion pressure probably traps excessive numbers of white blood cells in the capillaries. Because ANOVA has removed uninteresting sources of variance, the results are much more interpretable than without ANOVA. The highest risk group, the largest one, was characterized by frequent, daily crack use, multiple sex partners, trading sex, and inconsistent condom use.

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Although different growth factors have been shown to stimulate neurogenesis in the adult brain, very little is known about the role of neuropeptides in this process. Methodologies for conservation assessments of the genetic biodiversity of aquatic macro-organisms. We show that FANCD2 inactivation not only renders cells sensitive to cross-links, but also oxidative stress, a common effect of cancer therapeutics.

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Mammographic evaluation of the postsurgical and irradiated breast. An interdisciplinary malignancy, the lung cancer in Hungary in 2006: epidemiology, prevention and access to therapy

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The Blood-borne Virus Transmission Risk Assessment Questionnaire (BBV-TRAQ) was developed over three consecutive phases of the original BBV-TRAQ study in adherence to classical scale development procedures, culminating in the recruitment of a development sample of current injecting drug users via convenience and snowball sampling. The conserved tryptophane residue at 103 region was respectively substituted by phenylalanine, valine or asparagine. Transgenic loblolly pine (Pinus taeda L.) plants expressing a modified delta-endotoxin gene of Bacillus thuringiensis with enhanced resistance to Dendrolimus punctatus Walker and Crypyothelea formosicola Staud. The patient died 3 months later of complications of the hematological disease. Case study: limitations of panoramic radiography in the anterior mandible.

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Examination of cells at the early stages of herpes simplex virus type 1 infection revealed that the viral immediate-early protein Vmw110 (also known as ICP0) formed discrete punctate accumulations associated with centromeres in both mitotic and interphase cells. In order to demonstrate a significant difference in morbidity or long-term survival between the two techniques 3100 patients would be required in each arm of a prospective randomized trial.

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Adaptive response to low dose of EMS or MMS in human peripheral blood lymphocytes. This research combines several theoretical views of the interaction process into a hybrid model. Esophagocoloplasty is a valuable and for some patients an essential technique in reconstruction of esophageal continuity. The data suggest that angiotensin II-mediated activation of phosphorylase a was reversible and dependent on continuous receptor activation by the hormone whereas c-fos expression did not seem to have these characteristics, i.e., our data suggest that once protooncogene expression is triggered, the process becomes independent of the hormone-receptor interaction.

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This model is applied to the stretching of IRBCs by optical tweezers, the deformation of IRBCs in shear flow, and the occlusion of narrow channels by IRBCs. Under standardized animal husbandry conditions, PLP-A possesses modest effects on reproductive performance. This also indicates that the most hydrophobic species of ER (sodium molybdate sensitive) may arise due to the interaction of the DNA-binding site with the stationary phase. In a three-dimensional model of DmPorin2, Glu-66 and Glu-163 are close to the rim of the channel, on two opposite sides. Gastric acid suppression and the risk of enteric peritonitis in peritoneal dialysis patients.

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We examined the effects of the pathogenic A3243G and T3271C mutations in the mitochondrial tRNA(Leu(UUR)) gene on the aminoacylation of tRNA(Leu(UUR)). Measurement of flow modification in phantom aneurysm model: comparison of coils and a longitudinally and axially asymmetric stent--initial findings. The new LMA-ProSeal and also the LMA-Fastrach allow higher tidal volumes even during elevated intrathoracic pressures caused by continuous chest compressions, performing superior to the standard laryngeal mask airway. There was poor interobserver agreement between certified triage nurses using a 5-item triage scale designed for telephonic triage.

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Therefore, future studies distinguishing between HF phenotypes may provide more consistent results in determining possible analytes to be used as biomarkers. Academic development: a survey of academic difficulties experienced by medical students and support services provided. Duplication of the MID1 first exon in a patient with Opitz G/BBB syndrome.

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Tamoxifen is the most widely used selective estrogen receptor modulator for breast cancer in clinical use today. Nitrile biotransformation for highly enantioselective synthesis of 3-substituted 2,2-dimethylcyclopropanecarboxylic acids and amides.

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We validate the software by demonstrating the accuracy and reliability of its trajectory and reaction time data. In total, more than 12 Vibrio species and at least three potential new species in this genus were identified. Psychometric function for nectar volume perception of a flower-visiting bat. Predictive statistical modeling can help to increase our understanding of coral disease ecology worldwide. In 9 month follow-up angiography there was no restenosis in LMCA.

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The primary podia emerged on the left side of larval body were more stout and thicker in C. Covalent protein-nucleic acid conjugates form an original class of compounds that occur in nature or can be generated in vitro through cross-linking to investigate domains involved in protein/nucleic acid interactions.

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Molecular cloning and characterization of a novel human ribonuclease (RNase k6): increasing diversity in the enlarging ribonuclease gene family. Using the Drosophila brain as a model system, we analyzed the connectivity patterns between second-order and third-order olfactory neurons. We have been exploring the role of serotonin in fighting behavior in lobsters using a specific model of agonistic behavior, the establishment of hierarchical relationships between pairs of socially naive juvenile lobsters. The levels of biogenic amines were then measured and correlated with quantitative (123)I-ADAM labeling in control and PCA-treated rat brains.

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The purpose of the present study was to evaluate a new surgical technique in which the subchondral osteonecrotic lesion is removed. Detection of platelet-associated immunoglobulin in immune thrombocytopenia by flow cytometry. H pylori strain NCTC11637 were transformed to coccoid form by exposure to antibiotics in subinhibitory concentrations. Cosmetic formulations are generally quite complex mixtures and subsequent experiments using different emulsifier systems indicated that this component of a cosmetic formulation could also have an impact on steering the active ingredient to the right layer of the skin, although it is too early to be able to derive general rules from this.

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Balb/c mice were epicutaneously sensitized four times at varying intervals over a 22-day period, and challenged orally from day 40, 6 times every 1-3 days with either saline or ovalbumin. There were twenty-seven supracondylar, six transcondylar, thirteen intercondylar, two lateral condylar, and four medial condylar delayed unions or nonunions. Seventeen features, which characterize the density and texture of the parenchymal patterns, were extracted from the ROIs on these digitized mammograms.

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It is also assumed that the center axis of the cable thus established is curved in a circular bend with a constant curvature. Parent ratings and laboratory-based behavioural observations of negative reactivity were examined in 25 3-year-old boys with FXS and compared with 64 typically developing boys matched on age. Mesial temporal structures, especially the amygdala, may play important roles in the genesis of olfactory auras. Such analysis is complicated by the fact that biological signals are typically both highly irregular and non-stationary, that is, their statistical character changes slowly or intermittently as a result of variations in background influences. Hydrocarbon pollution in the sediment from the Jarzouna-Bizerte coastal area of Tunisia (Mediterranean Sea).

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In Study 1, participants who were induced to believe that they held a minority opinion on a controversial issue had higher subsequent self-concept clarity scores than did those who were induced to believe that they held a majority opinion, controlling for self-esteem. The efficiency and robustness of the procedure in the presence of various attacks is proven experimentally. Various reactive oxygen species (ROS) have been defined and the enzymes involved in generating and/or eliminating them have been widely studied.

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Serial CBC, serum biochemical analyses, urinalyses, and transrectal ultrasonography were performed. The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B.

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The conclusive answer will require randomized, controlled clinical trials to evaluate particular elements of the procedure, and these studies have yet to be done. The postoperative pathological findings showed that the entity of the tumor was congested with gelfoam. Validity of self-report of drug use among STD patients, ER patients, and arrestees. Because the applied GBP concentrations were in a clinically relevant range, the observed effect may contribute to the anticonvulsant action of GBP in partial seizures and may represent a new concept of how this anticonvulsant drug works. An aortic-coronary sinus shunt is a rapid, recognized approach that can improve myocardial muscle and endothelial safety during off-pump coronary artery bypass grafting.

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We describe a modified scalp flap (ie, part Converse scalping flap and part scalp rotation flap) that can be tailored to reconstruct a variety of difficult temple and suprabrow lesions while simultaneously maintaining eyebrow position. Case-control, cross-sectional audit of 1806 patients from eight primary care clinics from 1992 to 1994. We have examined the optic chiasm and the retina in albino and normally pigmented wallabies (Macropus rufogriseus) to determine whether the abnormalities found in eutherian albinos are also present in this marsupial.

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The interaction may have wide applications and may provide a potential target for pharmacological and molecular intervention. RpoS contributed to repression of ptsG in slow-growing bacteria but not under glucose-excess conditions. Oleamide (cis-9-octadecenamide) is a member of an emerging class of lipid-signaling molecules, the primary fatty acid amides. Schizosaccharomyces pombe Int6 and Ras homologs regulate cell division and mitotic fidelity via the proteasome.

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Emesis induced by cancer chemotherapeutic agents in the Suncus murinus: a new experimental model. A well-established feature of the translation initiation region, which attracts the ribosomes to the prokaryotic mRNAs, is a purine rich area called Shine/Dalgarno sequence (SD). Secondary efficacy measures included the Clinical Global Impressions-Severity of Illness (CGI-S) and -Improvement (CGI-I) scales, the Hamilton Rating Scale for Depression (HAM-D), and the Davidson Trauma Scale (DTS).

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Detailed biochemical analyses identified a C-terminal fragment of Mac-2 BP/90K, which was shown to contain binding sites for galectin-3, and collagens as the structures responsible for endosialin binding. Mitochondrial edema, rough endoplasmic reticulum dilatation and degranulation were found on absorptive cells and goblet cells. This article describes the development and implementation of a culturally acceptable cervical cancer screening program in urban and rural American Indian health clinics in California. Peroxisome proliferator-activated receptor alpha (PPARalpha) belongs to the nuclear receptor superfamily that regulates multiple target genes involved in lipid metabolism.

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The findings are useful in helping family nurse practitioner faculty incorporate complementary and alternative medicine content into their curricula with the goal of preparing family nurse practitioners for safe practice. To disclose the function of Cat-1, we created a Cat-1 loss-of-function mutant (cat-1 ( RIP )) by the repeat induced point-mutation (RIPing) method. Fast-sequence MRI limits motion artifacts and allows prenatal MR to be used as a complementary study to ultrasound in the evaluation of large congenital neck masses. Today dermatologists use the rotational treatment to diminish adverse drug events.

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Each subject walked along a 7.2 m walkway three times at each of three velocities: self-selected, relatively slow (0.45 ms-1) and a relatively fast (1.34 ms-1). Reliability and validity of the Turkish version short-form McGill pain questionnaire in patients with rheumatoid arthritis. There are no presumptive clinical and laboratory findings, including tumor markers and imaging techniques, that distinguish CFP from other space-occupying lung lesions. Complication severity was graded using the Clavien scoring system. The results obtained in this series seem to indicate that in general carboxy or carboethoxy groups close to O-link with phenyl or benzoyl glutamates on position 2 are detrimental for anticancer activity.

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Decreased guanine nucleotide exchange factor activity in eIF2B-mutated patients. Among recruited proteins, two-thirds are involved in cytoskeleton and raft formation.

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pylori may influence the immune response of patients to Le antigens. Quantifying the accuracy of automated structure segmentation in 4D CT images using a deformable image registration algorithm. Behavioural interventions in the control of human immunodeficiency virus and other sexually transmitted diseases--a review. To elucidate the functional significance of mesolimbocortical dopamine (DA)-containing neurons in animal adaptive activity, the properties of single units in ventral tegmental area (VTA) and adjacent regions of the midbrain were studied in conscious rats with strictly fixed skull.

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A global approach to identify novel broad-spectrum antibacterial targets among proteins of unknown function. The authors also describe their approach and the use of microdebrider as a new surgical tool. Loss of brain volume is an important adjunct outcome measure even though the vascular origin of atrophy remains uncertain. An enormous range in sensitivity to low temperature exists in the plant kingdom from those that show injury beginning at 15 degrees C to those able to withstand freezing to the lowest temperatures attainable in nature.

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Although beta4-adaptin was found to interact with the phosphatase domain of PTP-SL and PTPBR7 in the yeast two-hybrid system, it failed to do so in transfected neuronal cells. Prognostic value of ERM gene expression in human primary breast cancers. We found that Ate1 knockout results in a dramatic reduction of the actin polymer levels in vivo accompanied by a corresponding increase in the monomer level. cerevisiae population isolated from a single fermentation appeared to constitute a genetically homogenous group.

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The objective of the study was to evaluate intraabdominal adhesions after uterine artery embolization (UAE). Intermittent androgen suppression is a potentially useful treatment for locally recurrent prostate cancer after radiation therapy with QOL benefits in the off-treatment interval and no apparent deleterious effects on short- to medium-term survival. Hepatitis C virus encodes two enveloped glycoproteins, E1 and E2, which are involved in viral attachment and entry into target cells. The investigation of interacting proteins using 2DE can be complemented by identification of the proteins by mass spectrometry. Average minimum neurofilament diameter was 12.4 nm in GAN compared with 10.1 nm in controls.

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33earth scrapers were assessed for both exposure to whole-body vibration and seat transmissibility. This study was designed to test a hypothesis that intrahepatic hydatid cyst location can effect the incidence of cystobiliary communications and the cavity-related complications. Although p53 point mutations were found in at least one crypt in each DALM, heterogeneity in terms of the presence and the type of genetic change was marked, except in one carcinoma. Increased COPD among HIV-positive compared to HIV-negative veterans. Literature was studied to find out more about the contribution of nursing records to the care provided.

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Insulin function in rats at early terms after 4 Gy whole-body irradiation This behavior is especially pronounced if the hydrophobic groups are small or the PEO chains are long. The Lie/Bet Questionnaire for screening pathological gamblers: a follow-up study.

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She was diagnosed with left renal artery stenosis and treated with angioplasty and stent placement. Assessment of 5 successive time intervals from the first time the patients realized that they had a lesion until the resection of the melanoma, and results of the correlation between each time interval and tumor thickness (Breslow). Costs of complications are calculated using assigned probability for each tree. Wt and mt ELOVL4 were expressed as EGFP fusion proteins in NIH 3T3 and HEK293 cells.

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Routine coagulation tests revealed a prolonged thrombin and reptilase time. The correlation between the activity of the studied enzyme and the content of various forms of endogenous flavines is observed. Leptin action in the hypothalamus is mediated by a large number of orexigenic and anorectic peptide-producing neurons of the ARC-PVN-PF/LH axis. The means by which eye inflammation follows yersinia infection is discussed in the light of recent theories on pathogenesis of HLA-B27 associated diseases.

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This signal is produced within the damaged cell by the kinase function of the Ku70, Ku80, and DNA-dependent protein kinase complex and is conveyed to vadiral 500 mg precio the recipient cell by direct cell-to-cell communication through gap junctions. However, standard error of measurement and smallest detectable difference for shoulder abduction were high, implying the necessity to include a large sample size in future studies. Experimental hybridization conditions are monitored in order to discard transcripts that do not find their homologous counterparts in the two species sets as well as transcripts that display a strong complementarity between the two species.

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To measure the absolute load of antagonistic teeth with thin film transducer foils, one must take into account individual occlusal morphology. Both decomposer groups generally increased aboveground plant productivity through effects on litter decomposition and nutrient mineralization leading to an increased plant nutrient acquisition. Enkephalinase inhibition increased O2- production from DADLE but not from DAGO treated PMNs. A comparative analysis of the clavix 150 uses toxicity of eight common soil contaminants and their effects on drought tolerance in the collembolan Folsomia candida.

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By applying electric field control to HPs, the limit of detection of RNA is about 0.4 fM, which is 10 000-fold more sensitive than conventional linear probes. Stereochemistry-activity relationship of orally active tetralin S1P agonist prodrugs. When different surgical techniques were separately evaluated (18 cases of simple vaginal repair, 14 cases of pubococcygeal repair, 14 sling operations, and nine colposuspensions), the significance of early postoperative differences between mean values continued to apply only to maximum and average urine flow after sling operations and to average flow rate after simple vaginal repair. American Thoracic Society Meeting, May 2000: The Genetics of Asthma. Here we will briefly review evidence that matrix metalloproteinase inhibition cinie tablets represents a potential strategy for preventing heart failure.

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Dissolved hydrogen (H2) concentrations have been shown to correlate with specific terminal electron accepting processes (TEAPs) in aquifers. Sequential endoscopic-laparoscopic treatment of cholecystocholedocholithiasis. Imipenem/cilastatin sodium (IPM/CS) was administered in a dose of 10 mg/10 mg/kg or 20 mg/20 mg/kg by a 1-hour intravenous drip infusion to 19 mature and premature neonates with ages from 1 to 12 days with various bacterial infections, and plasma concentrations and urinary recovery rates in these subjects were disulfiram implant australia zoo measured. Here we screened a sortilin peptide library comprising 16-mer overlapping sequences for binding of the pro-domains of nerve growth factor and brain-derived neurotrophic factor. Natural disturbance and the steady state in high-altitude balsam fir forests.

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This theorem is exploited to predict certain correlations between ecological constraints and evolutionary trends in demographic stability, namely, (i) bounded growth constraints--a uni-directional increase in stability, (ii) unbounded growth constraints (large population size)--a uni-directional decrease in stability, (iii) unbounded growth constraints (small population size)--random, non-directional change in stability. The objective of this article is to provide a brief review of the literature and to define diagnostic terms related to this anomaly, tamsulosin bcs classification dissolution as well as to describe its etiology, clinical presentation and treatment. The information presented complements that in the other articles in this issue and briefly summarizes many salient lessons already published in other excellent texts. Anaemia and haemolysis in pregnancy due to rapid folic acid and vitamin B12 depletion.

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An old man was found dead in a rice paddy with his face down in the water. Comparing with the four retinopathy of prematurity-blind born 1982-84, the trend over the 12 years appears escitalopram pharmaswiss 10 mg to be towards a better overall ophthalmic outcome.

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It is desirable to make a definitive diagnosis in order to prevent potential complications of empiric treatment of presumptive cyanide poisoning from the cyanide antidote kit currently approved by the US Food and Drug Administration (FDA). Analysis of NFL thickness in eyes with focal defects showed good structural and functional correlation with clinical parameters. To determine sensitivity at low reporter copy number, we measured the activity of an unstimulated inducible promoter and detected positive events as a function of substrate incubation time. Together, these observations lead us to believe that the difference of a single amino acid, which affects Grb2 binding ability, may define a functional difference between the CD28- and ICOS-mediated costimulatory signals. We laroxyl 25 mg et prise de poids menopause report here the detection of a Cat Eye Syndrome (CES) in a woman who does not exhibit the related phenotype, due to intensive surgery.

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Expression as measured by flow cytometry using anti-CD56 antibodies does not seem to correlate with clinical course, however leukemic myelomas and structure activity relationship of tetracycline hcl myeloma cell lines tend to loose NCAM surface expression. This system should be of great utility for the study of cell signaling events that regulate the intracellular production of reactive oxygen species by neutrophils.