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Candistat (Itraconazole)

Candistat is triazole antifungal agent. As with other triazoles, it has five-membered ring structures containing three nitrogen atoms. It is available in oral capsule form (since 1992), oral solution in cyclodextrin (since 1997) and intravenous formulation in hydroxy-propyl-beta-cyclodextrin (since 1999). In its capsule and oral solution form, Candistat is marketed as Candistat by Janssen Pharmaceuticals. The intravenous formulation is marketed by Ortho Biotech. Candistat is a highly lipophilic compound. While it achieves high concentrations in fatty tissues and purulent exudates, its penetration into aqueous fluids remains very limited. Gastric acidity and food influence the absorption of oral formulation.

Other names for this medication:
Itraconazole, Sporanox, Fulcover, Icoz, Candistat,

Similar Products:
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Candistat solution is an azole antifungal medication used to treat certain fungal infections, including infections of the mouth, throat, and esophagus (oropharyngeal/esophageal candidiasis). OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This drug may also be used to prevent certain fungal infections in patients with HIV.

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Uptake of siderophores and vitamin B(12) through the outer membrane of Escherichia coli is effected by an active transport system consisting of several outer membrane receptors and a protein complex of the inner membrane. Genetic structure of the poplar rust fungus Melampsora larici-populina: evidence for isolation by distance in Europe and recent founder effects overseas. Several simulations were performed to present the ability of the computational method to focus through, for instance, curved and plane surfaces between two media (acrylic-steel). Bone marrow transplantation from an unrelated donor in patient with congenital heart diseases

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Monkeys are an animal model in which MV infection most closely resembles the human disease. Antivascular and antitumor evaluation of 2-amino-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-4H-chromenes, a novel series of anticancer agents. Anatomical organization of motoneurons and interneurons in the mudpuppy (Necturus maculosus) brachial spinal cord: the neural substrate for central pattern generation. Seventeen infants had normal US and EMG findings but pathologic cranial magnetic resonance imaging or metabolic/genetic tests.

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Delayed spinal cord injury after high-voltage electrical injury. To evaluate marginal bone loss on the individual and tooth level, with focus on the importance of the baseline marginal bone level.

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Reactive oxygen species as mediators of angiogenesis signaling: role of NAD(P)H oxidase. The platinum(II) complex loaded in the channel of SBA-15 is stable, and the photosensitized oxidation occurs efficiently.

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market in part because of the occurrence of colon ischemia in treated patients. Also, the correlation between raters was exceptionally high indicating that each audiologist rated the presence of rust for each battery in a very similar manner.

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These stimulating agents induced early (CD69 and CD71) and late (CD25 and HLA-DR) activation markers to varying antigen densities, indicated different cytokine profiles, and showed differential inhibition with dexamethasone (DEX), an inhibitor of early signaling events. The results revealed that it is possible to predict tetanic force with high accuracy by using regression equations. Successful unrelated cord blood transplantation using a reduced-intensity conditioning regimen in a 6-month-old infant with congenital neutropenia complicated by severe pneumonia. To further this objective, we have evaluated a reverse line blot (RLB) assay, which simultaneously detects the principal tick transmitted protozoan and rickettsial cattle pathogens, in different epidemiological scenarios in Uganda. Seasonal dynamics of shallow-hyporheic-zone microbial community structure along a heavy-metal contamination gradient.

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In the present study, these previous observations were extended by examining micronucleus induction with a larger number of compounds in both CTLL-2 and CTLL-2 bcl2 cells and measuring apoptosis with annexin V-FITC. Two protein-Congo red complexes were found after heating lambda chain in the presence of Congo red. Intravenous injection of 5 IU oxytocin immediately after delivery of fetal anterior shoulder is the treatment of choice for prevention of PPH in patients with natural course of labor. Hydrophobic bile acids produce hepatotoxicity in vivo and in vitro.

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Odds ratio (OR) of bone fracture after incidental fall associated with presence of hyponatremia. The purpose was to determine if an increase in thermal activity had taken place since an earlier airborne survey in 1966. On the other hand, with this procedure there are complications such as band slippage, erosion, balloon problems and tubing problems, which have required reoperations for remedy. In many cases, an otorhinolaryngologist can be the first physician to examine a patient with tetanus.

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Some transplant centers consider paternal HLA antigens as unacceptable mismatches for mothers awaiting kidney transplantation. The stiffness value of tumor-free hepatic parenchyma was calculated.

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Previous research has generally found that racial/ethnic differences in breast cancer stage at diagnosis attenuate when measures of socioeconomic status are included in the analysis, although most previous research measured socioeconomic status at the contextual level. Knowledge locally generated through pilot projects is crucial for innovative health policy. With a rapid growth in the number of publications on analytical applications of RTILs, it appears that in the near future these neoteric solvents are definitely going to be a permanent feature in analytical chemistry. Although these observations suggest direct hindbrain action of leptin on feeding and body weight, the possibility that hindbrain leptin administration also activates the Janus kinase/signal transducer and activator of transcription 3 (STAT3) signaling in the hypothalamus has not been investigated. AHPCs were transplanted 24 h after SC ablation, or 5, 7 or 14 days following optic nerve (ON) transection.

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Criticism of psychiatric care of the most severely ill patients--resources and education are demanded Although these two endosomal pathways operate independently of viral replication, little is known about the detection of actively replicating viruses in plasmacytoid dendritic cell (PDC). The program serves individuals who use the outpatient clinic at the state-run public hospital in central Louisiana.

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These results indicate that plant Aurora kinases phosphorylate not only Ser10, but also Ser28 of histone H3 in vivo. The wrinkle pattern with expression at baseline was compared with the pattern without expression at 8 years. Included in the review were recent papers exploring the mechanisms linking maternal nutrition with impaired foetal growth and later obesity, cardiovascular disease, hypertension and diabetes in humans and animals.

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Cranio-cerebral erosion is a well-known complication of calvarian fracture with underlying dural tear and cerebral injury in infancy and early childhood. Independent variables are demographics, health needs (arthritis, other medical conditions, functional health), and economic access (income, assets, education, and health insurance).

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Margins of safety for small mammals and amphibians appear to be large under any probable exposure scenarios, however our results indicate high variability in responses among species. The problem and promise of scale dependency in community phylogenetics. Feeding external Phe to wild-type callus tissue and seedlings resulted in Trp accumulation, demonstrating a connection between Phe accumulation and Trp pool size. The risk was substantially lower for patients who had an orthotopic neobladder. Population cell density itself strongly affected the expression of porin protein genes, especially ompF, and hence the permeability of the outer membrane.

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Hyalomin-A and -B were both found to potently scavenge free radical in vitro in a rapid manner and inhibited adjuvant-induced inflammation in mouse models in vivo. Increased bronchial responsiveness is a feature of symptomatic asthma, and it predicts the onset of wheezing. Opinions of UK specialists about terminology, diagnosis, and treatment of atypical facial pain: a survey.

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Sedimentation velocity, multi-speed method for analyzing polydisperse solutions. Both viruses trigger stress pathways in the cells they infect, sometimes culminating in the death of the host.

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The number of cigarettes/day was introduced into the model for smokers and a significant negative coefficient was obtained for this variable. Based on the hypothesis that both psychotic and manic disorders reflect gating impairments, the present study was aimed at the assessment of the impact of SD on the behavioural model of prepulse inhibition (PPI) of the startle reflex, a reliable paradigm for the study of informational filtering. Visceral artery aneurysm: risk factor analysis and therapeutic opinion.

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Using systemic administration of NO synthase (NOS) inhibitors to chronically inhibit NO production, we increased neural precursor proliferation in the subventricular zone as well as neurogenesis in the olfactory bulb, without modifying the number of mitotic cells or the granular cell layer thickness in the dentate gyrus. There is currently no evidence to support their routine use in pancreatic surgeries performed for other indications. We propose that rab11BP is an effector for rab11, whose association with this GTP-binding protein is dependent on the action of another membrane-associated factor that promotes the unmasking of the rab11-binding site in rab11BP.

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The phosphorylation mimetic mutant MST1 T387E blocks H2O2-triggered FOXO3 nuclear translocation and apoptosis. The post-transcriptional gene silencing in animals and plants is called RNA interference (RNAi). Moreover, information is provided on the mobile genetic elements carrying Cm or Cm/Ff resistance genes to provide a basis for the understanding of the distribution and the spread of Cm resistance--even in the absence of a selective pressure imposed by the use of Cm or Ff. Regulation of preproenkephalin expression in astrocytes: is there a role for glia-derived opioid peptides in reactive gliosis?

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The 22q11 deletion syndrome is a differential diagnosis in children with a variety of symptoms and signs including congenital malformations, developmental delay and speech abnormalities. Befriending carers of people with dementia: randomised controlled trial. Social networks and homelessness among women heads of household.

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Non-contrast and contrast-enhanced CT images were recorded and reviewed separately. The constituent glycosaminoglycan chains of fluorotic dentin were of lower molecular size and showed the additional presence of dermatan sulfate and heparan sulfate by comparison to nonfluorotic controls, where only chondroitin-4-sulfate was detected.

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We evaluated the susceptibility of 14 glioma cell lines to infection and killing by mutant strain VSV(deltaM51), which contains a single-amino acid deletion in the M protein. Tc-99m sestamibi imaging of brown tumors of primary hyperparathyroidism. A performance improvement programme at a public hospital in Sri Lanka: an introduction.

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Metabolic control affects plasma lipid and apolipoprotein levels in women, but not in men, with IDDM. To reduce friction between orthodontic stainless wires and bracket by coating the wire with nickel-phosphorous electroless film impregnated with inorganic fullerene-like nanoparticles of tungsten disulfide (IF-WS(2)) which are potent dry lubricants. Using CSGE, a single nucleotide polymorphism was discovered in exon 2 and another in intron 2 of the gene. Some critical dental characters, such as a postprotocingulum on upper teeth, consistently reveal a primate status for the azibiids. Array construction presents technical difficulties and tissue arrayers are expensive, particularly for small and medium sized laboratories.

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The stability of 3-9 under acidic and basic conditions, the effect of substitution at C-2 position, and potential biological activities are discussed. The pharmacokinetics of CBDCA following ip administration of alpha-TCP-CBDCA were studied. Human microvascular endothelial cells (HMVECs) and human umbilical vein endothelial cells (HUVECs) were stimulated with Fkn and analyzed by Western blotting or stained with Alexa Fluor 488 phalloidin for F-actin to characterize the time frame of cytoskeletal rearrangement.

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If the system were linear, such convergence would increase the neural noise enough to overwhelm the tiny rod signal. Histology and SEM confirmed the diagnosis established with the microscan which also enabled a 3D analysis of the sample and study of the trabecular architecture of the intersomatic graft. The other possibility is to modify current immunotherapy administration. Preparation of an activity-inhibiting monoclonal antibody against human placental aromatase cytochrome P450.

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Cardiovascular magnetic resonance features of caseous calcification of the mitral annulus. One important use of the technology is the sequencing of small non-coding regulatory RNAs and the identification of the genomic locales from which they originate. Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes.

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A case of 73-year-old woman with postmastectomy lymphedema of the right arm and subsequent lymphangiosarcoma is reported. Because the interpretation of such measures is therefore ambiguous, measures of diminished affective experience may have greater validity in research on affective deficits in schizophrenia than measures of blunted affective expression.

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We found that freshly isolated monocytes from SLE patients had an increased expression of CD11b. The present research used the illusion-of-control paradigm to examine the relationships among obsessive-compulsive disorder (OCD) symptoms, behavioral control attempts, and illusory sense of control. Interestingly, v-Fos differs from other common oncoproteins in not requiring calpain activity for actin/adhesion remodelling or migration of v-Fos transformed cells. Effects of cerebral cortical and striatal lesions on autotomy following peripheral neurectomy in rats.

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We have previously shown that Escherichia coli BJ4 has similar doubling time in mice that are mono-associated (having only the inoculated E. Posttransplantation skin prick test results were positive for peanut, cashew nut, and sesame seed, and the donor had allergen-specific IgE antibodies to the same 3 allergens. Attention modulates the blood oxygen level dependent response in the primary visual cortex measured with functional magnetic resonance imaging. Individual differences in fear: isolating fear reactivity and fear recovery phenotypes. Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer.

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Deep hypothermia during ischemia improves functional recovery and reduces free-radical generation in isolated reperfused rat heart. Late Perthes disease after satisfactory treatment of congenital dislocation of the hip. Here we show that insulin is expressed in and secreted from human ejaculated spermatozoa. Women on methadone maintenance on high doses should be counselled to wean breast-feeding gradually. Decreased endothelin expression in the contralateral kidney may facilitate trophic changes and compensatory increased blood flow.

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The release mechanism was described and found to be non-Fickian for all formulations. Indole-3-carbinol (I3C) has been found to act against several types of cancer, while ultraviolet B (UVB) is known to induce the apoptosis of human melanoma cells.

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Interestingly, the number of macrophages was significantly increased during the acute phase, whereas T cells were significantly increased in both the acute and chronic phase in C57BL/6 mice. This bond is nearly apolar and its contribution to the surface dipole is relatively small. The aim of the study was to use erythrocyte E-6TGN, methylated mercaptopurine (MeMP) metabolites, and thiopurine methyltransferase (TPMT) measurements in a clinical setting to determine the clinical outcome in relation to thiopurine metabolism. Aldosterone is the basic regulator of extracellular fluid volume and electrolyte balance. Ossified posterior longitudinal ligament: management strategies and outcomes.

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Relationships between health, demographic factors, evaluations of general practice care, and patient self-reported enablement were estimated using multiple regression. Measurement of vertebral rotation in idiopathic scoliosis using the Perdriolle torsionmeter: a clinical study on intraobserver and interobserver error.

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These findings probably suggested a case of delayed puberty associated with sensorineural hearing loss and anosmia. Interdurally localized dermoids presenting with ophthalmoplegia is uncommon. FcepsilonRI signals by activating proximal non-receptor type of protein-tyrosine kinases, alopron medication Lyn, Syk, Btk and Fyn.

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