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Karum (Clopidogrel)
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Clopidogrel

Karum is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. Karum is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial disease. It has been shown to be superior to aspirin in reducing cardiovascular outcomes in patients with cardiovascular disease and provides additional benefit to patients with acute coronary syndromes already taking aspirin. Karum was granted FDA approval on 17 November 1997.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

Similar Products:
Duinum, Gemfibrozil, Aventyl, Imigran, Adnil, Desval, Clavinex, Zovanta, Anafranil, Improvox, Lavestra, Novofen, Fluzone, Aurex, Selis, Procor, Tromar, Ramace, Donaren, Bilem, Cital, Ciprofloxacina, Cytoxan, Amoxiclav, Clavaseptin, Ramicomp, Ceftinex, Tonaril,

Karum is used alone or with aspirin to prevent serious or life-threatening problems with the heart and blood vessels in people who have had a stroke, heart attack, or severe chest pain. This includes people who have percutaneous coronary intervention (PCI; angioplasty; a type of heart surgery) that may involve inserting coronary stents (metal tubes surgically placed in clogged blood vessels to improve blood flow) or who have coronary artery bypass grafting (CABG; a type of heart surgery). Karum is also used to prevent serious or life-threatening problems with the heart and blood vessels in people who have peripheral arterial disease (poor circulation in the blood vessels that supply blood to the legs). Karum is in a class of medications called antiplatelet medications. It works by preventing platelets (a type of blood cell) from collecting and forming clots that may cause a heart attack or stroke.

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Weight loss in obese men by caloric restriction and high-dose diazoxide-mediated insulin suppression. An unanticipated interaction between Angioguard and abciximab was seen, with combination therapy better than no treatment or either treatment alone. Leg blood flow during submaximal cycle ergometry is not reduced in healthy older normally active men. The long- and short-term outcome of living-donor liver transplantation. We analysed which component(s) of NCEP MS criteria had greatest predictive value for mortality.

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This study prospectively examined the effects of anger expression on incidence of cardiovascular disease. The aim of the present study was to evaluate the analgesic effects of intra-articular morphine after knee arthroscopy.

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To evaluate the efficacy of patient and staff cohorting to control vancomycin-resistant enterococci (VRE) at an Indianapolis community hospital. Furthermore, the OSM-induced suppression of adiponectin expression and dedifferentiation of adipocytes were ameliorated by WHI-P131 or U0126, but not by AG490. Some other cationic peptides, copurified as minor components, were also characterised by N-terminal sequencing, mass spectrometry and antibacterial activity determination. Levels II-IV had been removed in them all, and their neck specimens were marked according to the levels of the neck.

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Vascular-targeted photodynamic therapy (padoporfin, WST09) for recurrent prostate cancer after failure of external beam radiotherapy: a study of escalating light doses. Therefore, the controlled release of different growth factors from scaffolds appears to have great potential to orchestrate tissue repair effectively. The present study in rabbits was performed to assess the effects of mechanical overload on cardiac sympathetic neuronal function and beta-adrenoceptor density, in relation to left ventricular function.

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Temperament and its implications for neuroimaging of anxiety disorders. Subjects treated with timolol had an increase in retinal vessel width compared to the placebo group significant especially for the superior temporal vein. Skillful resuscitation of the newborn, especially those at the border of neonatal viability. Free radical-mediated damage of blood and its inhibition by antioxidants.

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A model is discussed in which the levels of expression of the structural genes reflect the outcome of competition between the countervailing regulatory activities of the H-NS and VirB proteins. An approximately 180 kb tandem duplication was found in a patient with autistic disorder and cognitive delays, and in his mother and younger brother who have speech delay.

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On necropsy, VPB animals had greater lungwet-to-dry weight ratios compared to APB. Our goal was to compare serum human chorionic gonadotropin (hCG) levels in singleton pregnancies achieved following IVFET with those achieved following spontaneous conception.

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These residues form an elongated charged factor Xa binding cluster on the factor Va surface. The implementation literature suggests that a single policy decision, such as mandating a specific EBP, is unlikely to result in sustainable implementation. Alternate interventions focused on the specific cognitive deficits of individuals with bipolar disorder may be necessary to enhance vocational functioning after a depressive episode. The COX-2 index was determined from the band Adj volume counts ratio of COX-2 to constitutively expressed actin.

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Confidence intervals in which assay bias are taken into account, form a better guideline for detection of possible persistence or recurrence of DTC than functional sensitivities. Freezing tolerance is an important factor in the geographical distribution of plants and strongly influences crop yield.

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Closely matched human leukocyte antigen recipients, those older than 65 years, and recipients with donors more than 40 years younger were at higher risk for GVHD. Structural development studies of thalidomide showed that some N-2,6-dimethylphenylhomophthalimide analogs possess NOS-inhibiting activity. He was seen for 23 sessions of individual process-experiential/emotion-focused therapy. Total duodenal diversion in the treatment of complicated peptic oesophagitis.

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To establish a quick and reliable method to identify Streptococcus oligofermentans, a new species of oral streptococci. STI testing using self-collected vaginal specimens is highly acceptable to adolescent girls, and can dramatically increase the detection rate for these three treatable infections when pelvic exams are not performed. Both carotid arteries of the patients were examined with color Doppler ultrasonography before and after the placement of a permanent pacemaker, and the results were discussed.

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Children undergoing bone marrow transplantation (BMT) are prone to develop severe gastrointestinal (GI) complications and metabolic imbalance which consequently impair their nutritional status. The modified residue is located at position 88 in ribosomal protein S12 from Escherichia coli, a phylogenetically conserved protein that has been implicated in maintaining translational accuracy of the ribosome. Various thicknesses of the Lucite sheets were utilized to simulate scattering tissues. As expected, no significant difference in basal level of skin GPx activity was detected in the 3 lines of tg-MT-GPx mice investigated compared with non-transgenic controls.

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A group of at least 9 distinct immunoreactive polypeptides could be characterized by Western blot analysis. The association between the occurrence of postoperative atrial fibrillation and preoperative, intraoperative, and postoperative data from the total study population and the amiodarone and placebo subpopulations were explored using multiple logistic regression analysis. We studied these phenomena with implants superficially doped with 14carbon, specially prepared using the usual production processes of these materials.

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Atypical cribriform lesions of the prostate: relationship to prostatic carcinoma and implication for diagnosis in prostate biopsies. To identify potential endothelial precursors, we immunolabled kidneys with antibodies against the vascular endothelial growth factor receptor, flk-1. Orphans, AIDS, and the Millennium Development Goals: models and capacity to act

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Eighteen patients with essential hypertension participated in this study. The interviewed women required more knowledge about preventing vertical transmission of HIV/AIDS. Anti-hormones in obstetrics and gynaecology: ethical and social issues. Clinical values of estrogen receptor (ER) as a prognostic factor in breast cancer 13C-formylation for improved nuclear magnetic resonance profiling of amino metabolites in biofluids.

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Given the crucial role of the nuclear envelope in gene regulation and cellular organization, it is not surprising that its biogenesis and organization have become active research areas. Mecamylamine injection triggered comparable withdrawal signs in wild-type and in beta2-/- mice, whereas the beta4-/- mice displayed significantly milder somatic symptoms.

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However, there are disadvantages and ambiguities associated with these techniques because all of them require either separate probes, separate PCR amplifications, or complicated post-PCR manipulations. Inspired by the subwavelength resolution capability of the super-resolution near-field structure, a simplified optical structure was proposed to investigate the complicated near-field optical interactions between random silver nanoparticles and evanescent waves from a zeroth-order grating. We here report a case of subcutaneous gallstone as a rare clinical presentation of the already uncommon cholecystocutaneous fistula. Platinum complexes of naphthalene-1,8-dichalcogen and related polyaromatic hydrocarbon ligands. The mutation in the mdx2cv mouse was found to be a single base change in the splice acceptor sequence of dystrophin intron 42.

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The results indicate that SAF-1 is involved in the regulation of MMP1 gene expression and it is highly abundant in the articular cartilage chondrocytes of OA patients. CPREzy improves performance of external chest compressions in simulated cardiac arrest. In this chapter we outline procedures for the immobilization of the prototype GPCR structure, rhodopsin or the G-protein alpha and betagamma subunits, for analysis of the molecular interactions initiating G-protein signaling. The goal of this study was to compare the pharmacokinetics of the new CR formulation and an IR formulation of simvastatin after single- and multiple-dose administration in healthy Korean subjects.

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