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Lafigin (Lamotrigine)
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Lamotrigine

Lafigin was originally developed as an antiseizure drug because of its ability to reduce folate levels. At the time of the drug's development, it was thought that folate depletion would treat epileptic activity. Although this is now known to be incorrect, the drug did serendipitously treat seizures effectively. Currently, pharmacologists understand that Lafigin reduces neuronal activity via a variety of mechanisms. The most commonly accepted mechanisms of action are enhancement of sodium channel inactivation and possible inhibition of synaptic glutamate release. In early studies, patients with epilepsy who were taking Lafigin reported increases in a subjective sense of well-being, and this led to its exploration as a psychotropic drug. From a neuropsychiatric standpoint, Lafigin appears to inhibit uptake of serotonin, dopamine, and noradrenaline.

Other names for this medication:
Lamotrigine, Lamictal, Daksol, Epitec, Flamus, Labileno, Lafigin, Lamal, Lambipol, Lamez, Lamictin, Lamidus, Lamirax, Lamitor, Lamitrin, Lamogine, Lamolep, Lamotrigin, Lamotrigina, Lamotrix, Lomarin, Meganox,

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Lafigin is a medicine used to treat epilepsy.

It can also help prevent low mood (depression) in adults with bipolar disorder.

Lafigin is available on prescription. It comes as tablets that you can either chew or dissolve in water to make a drink.

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Gallstone abscess: a delayed complication of spilled gallstone after laparoscopic cholecystectomy. The multifactor dimensionality reduction (MDR) method has been proposed and implemented by Ritchie et al. Receptors are themselves phosphorylated and dephosphorylated by cellular kinases and phosphatases. Beta-adrenoceptor subtype expression in human placenta and umbilical arteries in normal and preeclamptic pregnancies. In contrast to electrolytical detachment, no foreign substances are released to the blood stream.

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C957T DRD2 polymorphism is associated with schizophrenia in Spanish patients. Anorectal incontinence: aetiology, pathophysiology and evaluation. The popularity of immediate post-partum IUD insertion in countries as diverse as China, Mexico, and Egypt support the feasibility of this approach. This is the first reported sediment record of the silica-depletion sequence for the Great Lakes. There was preliminary evidence that suggests that cue exposure therapy may be more effective for patients with severe alcohol dependence.

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The insulin-like growth factor-I (IGF-I) is an important polypeptide hormone under investigation for body metabolism study and for doping detection. Evidence for the participation of the G1 cyclins D and E in breast cancer is summarized, including transgenic and knockout mice, transfections, and expression patterns in cohort studies. Serum levels of thyroid hormones, estradiol and testosterone were decreased in PCB treated animals. Oesophageal aspergillosis in a case of acute lymphoblastic leukaemia successfully treated with caspofungin alone due to liposomal amphotericin B induced severe hepatotoxicity. Participation in active games may present a substitute to decreased involvement in moderately active work and play activities.

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Evidence of inappropriate use of vancomycin in a university affiliated hospital in Brazil. In the context of established relations between plasma selenium and risk of cancer and mortality, and recognizing the important functions of selenoprotein P, these results provide important evidence for deriving estimated average requirements for selenium in adults. However, these shifts did not coincide with plasma and urine bile acid concentrations and histological and functional changes. A rapid automated SSCP multiplex capillary electrophoresis protocol that detects the two common mutations implicated in hereditary hemochromatosis (HH).

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A management plan based on probability for DVT that avoids the need for urgent diagnostic imaging is safe and feasible in the emergency department setting. Clinico-morphologic and biomicroscopic parallels in the management of patients with various forms of purulent paranasal sinusitis and methods of correcting microcirculatory disorders We conclude that the fatty acid composition of PL can be a crucial determinant for the clearance of TRL during the postprandial metabolism of fats. Results are discussed in the context of organizational reform in the police service. The cytological trend is compared with that of histologic and clinical findings of HPV lesions on the basis of data prospectively collected.

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During the last 5 years (2004-2009), 11 soil gas emission surveys have been carried out at the Municipal Solid Waste landfill of Legoli (Peccioli municipality, Pisa Province, Italy) by means of the accumulation chamber method. In general, CASI medians and means were higher and correlations among CASI measures tended to be lower than those obtained with paper-and-pencil and mixed mode assessment, and CASI variances were lower.

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To meet this challenge, a group of nurses took a leadership role in developing an oral care guide. However, the association between leptin and metabolic syndrome independently of body fat and body fat distribution has not been evaluated in healthy elderly people. We explored the effects of human immunodeficiency virus-1 (HIV-1) and its Tat transactivator on these primary antigen-presenting cells using DNA microarray analysis and functional assays.

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Thus cellular mechanical dysfunction after hypertrophic stimuli may or may not be mediated microtubule remodeling depending upon the experimental model and conditions. Concerning that results it is possible to create clinical studies in order improve the diagnostic procedures ant therapy of secretory otitis media. Initial data suggest that elastography can improve the specificity of ultrasound in differentiating benign and malignant breast lesions. These findings show that avian cranial neural crest use Eph and ephrin receptors as other vertebrates in guiding migration.

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To clarify the physiological significance of the pulmonary artery index (PAI), we examined the relationship between PAI and physiological properties of the pulmonary vascular bed. A clear distinction between differently substituted celluloses regarding mobility and selectivity is observed, and capillary electrophoresis shows to be a technique capable of separating mixtures of intact cellulose derivatives independent of molecular weight or hydrodynamic radius. An unprecedented Au-Ag alkynyl-diphosphine aggregate, obtained via CO-reduction of a mixture of simple reagents, exhibits intense room-temperature phosphorescence free from O(2) quenching, and serves as an excellent phosphorescence dye suited for both one- and two-photon imaging in human stem cells. No significant duodenal epithelial changes were found in alcoholics, despite an evident reduction in the enterocyte turnover. Antisense RNAs in prokaryotic systems often inhibit translation of mRNAs.

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Anti-TNF alpha agents in patients with rheumatoid arthritis refractory to conventional therapies ASIAN-AMERICAN SCIENTISTS: New Breed of Protester Asks: Why Not Us? Finally, in situ hybridization was used to examine colocalization of GLP-1 receptors with neuropeptide tyrosine and pro-opiomelanocortin neurons. Selective angiography is useful to diagnosis the central hemangioma of mandible, and the complete curettage of the hemangiomas in the body of mandible is the most appropriate operation for children. To explain the strong association between HLA-B27 and ankylosing spondylitis, we suggest that the release of beta(2)-microglobulin (beta(2)m) from a subpopulation of cell surface-expressed HLA-B27 molecules leads to beta(2)m-deposition within synovia and to the initiation of an inflammatory process, which culminates in destructive spondyloarthropathy.

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These species-related differences in cellular synaptosome-associated protein of 25 kDa distribution suggested that the synaptosome-associated protein of 25 kDa homologue, synaptosome-associated protein of 23 kDa, is also expressed in the rat choroid plexus, which was confirmed by reverse-transcriptase polymerase chain reaction. In the interval between 10 and 30 years after diagnosis, patients are nearly as likely to die of ACC as from all competing causes combined. Such guidelines are identical to marketing approval documents in France. A lower hip circumference could reflect either lower fat mass or lower muscle mass.

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Mapping the organizational culture research in nursing: a literature review. Methotrexate-induced interstitial pneumonitis in a child with acute lymphoblastic leukemia Implementation and integration of regional health care data networks in the Hellenic National Health Service. A specific, sensitive, accurate, and precise capillary gas chromatographic assay for determining trace levels of hydroxylamine, a well-known mutagen, in propionohydroxamic acid bulk drug and oral preparations is described. The calcium antagonist flunarizine is shown to be able to prevent particle aggregation, membrane aggregation and blebbing resulting from elevated calcium concentrations.

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A 66 year old female presented with a symptomatic solitary non-parasitic liver cyst. Esophageal carcinoma can be managed primarily with either a surgical or radiotherapeutic (non surgical) approach.

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Laminin, a major glycoprotein integrated into basement membranes, is observed in angiogenesis and tumorigenesis. BmBKTx1 is a 31-amino acid peptide identified from the venom of the Chinese scorpion Buthus martensi Karsch, blocking high-conductance calcium-activated potassium channels.

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Concentration and distribution of 5-Fu in tissues monitored by 14C-isotopically tagged 5-Fu Study on the interaction among pyronine Y, potassium bromate and naphthols by absorption, three-dimension fluorescence and resonance light scattering spectra and their application. The Fe-enriched diet prevented Cd-induced histopathological changes as well as deprivation of tissue Fe and lipid peroxidation. Similarly, early trauma enhanced intestinal mucosal dysfunction to an acute stressor in adult rats and the response is prevented by peripheral injection of CRF antagonist.

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To determine test-re-test reliability of the VIrtual Planning Test (VIP) in a group of individuals with traumatic brain injury (TBI). Loss of long-duration response to levodopa over time in PD: implications for wearing-off.

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Growing evidence supports a role of metabotropic glutamate receptors (mGluRs) in ethanol reinforcement, ethanol seeking, and ethanol withdrawal. Loss aversion in non-risky choices has not been studied in schizophrenia. Ventilated patients in the intensive care unit (ICU) often develop exposure keratopathy. Much is known about opioid metabolism, which is critical in administering these agents to the elderly.

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The agulhas current during the late pleistocene: analysis of modern faunal analogs. Validation of a Spanish version of the Short Musculoskeletal Function Assessment Questionnaire (SMFA). Simultaneously, expression of HOXB2 mRNA had decreased significantly by 24-48 h after transfection.

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A total of 407 patients diagnosed with acute CVD and 158 control subjects were genotyped for the A54T polymorphism using a PCR-RFLP method. Differential diagnosis of chronic fatigue syndrome and major depressive disorder. Analysis of the utinor tablets computers self-serving bias yielded activation in the dorsal anterior cingulate and in the dorsal striatum, suggesting a rewarding value of these attributions. Screening programs and early intervention can provide enormous economic and social benefits.

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Dendritic cells (DC) represent a heterogeneous cell family of major importance for innate immune responses against pathogens and antigen presentation during infection, cancer, allergy and autoimmunity. We also present the various in vitro assays used to evaluate modulation of CYP enzyme activity. Transport steps between the compartments and the extracellular space represent 281 reactions, of which 161 are unique. We also show that weakly nonlinear losartan overdose fatal waves can still be time reversed under weak dissipation. Urinary excretion of sucrose and fructose as a predictor of sucrose intake in dietary intervention studies.

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Rubber workers demonstrated significantly lower ventilatory capacity measurements compared to predicted. Medical needs of people with intellectual disability require regular reassessment, and the provision of client- and carer-held reports. The 3 major spinal manifestations of RA in the cervical spine are basilar invagination, atlantoaxial instability, and subaxial subluxations. Cutaneous leiomyomas are classified in 3 types regarding their origin: multiple or solitary piloleiomyoma, arising from arectores pilorum muscles, solitary genital leiomyoma, arising tussionex schedule drug tramadol from the dartoic, vulvar, or mammillary muscles, and solitary angioleiomyoma, arising from the vein muscles. Air pollutants of iron- and steel-making operations have historically been an environmental and health hazard.

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We evaluated the SQuISH protocol against a riboprobe-based ISH procedure by comparing the mRNA expression levels in the brain for two transcripts, insulin receptor substrate p53 (IRSp53) and Calsenilin. The widespread use of the two libraries as an integral part of the rat genome project has led to the database annotations for many clones, providing rat researchers with a rich resource of BAC clones that can be screened in silico for genes of interest. We recently described a method for the generation of a large human domain antibody repertoire involving citalopram fda black box warning for abilify combinatorial assembly of CDR building blocks from a smaller repertoire comprising a high frequency of aggregation-resistant antibody domains. Color Doppler sonography of 23 histologically proven masses in 22 patients was performed.

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