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Lopo (Losartan)

Local bone RAS functionally played a role in the development of type 1 diabetic osteoporosis, and Lopo had no bone-sparing function in diabetes mice because of enhance skeletal RAS activity. Lopo treatment resulted in improvement of myocardial function and suppressed cardiac and renal fibrosis compared with the diabetic group.

Other names for this medication:
Losartan, Cozaar, Lortaan, Losacar, Losakind, Lostat, Omnitan, Losium, Angilock, Angizaar, Aratan, Araten, Cardon, Cartan, Cormac, Corodin, Corus, Cosart, Covance, Eklips, Etan, Fensartan, Fortzaar, Hilos, Lacine, Lara, Larb, Lavestra, Lifezar, Loben, Logika, Loortan, Lopo, Lorista, Losa, Losacor, Losan, Losap, Losaprex, Losar, Losart, Losartanum, Losartas, Losatan, Losatrix, Lostan, Lotan, Lotar, Lotim, Lozap, Lozar, Lyosan, Mozartan, Niten, Normatens, Ocsaar, Osartil, Ostan, Prelow, Prosan, Rasertan, Rasoltan, Repace, Resilo, Rosatan, Sarilen, Sarlo, Sarvas, Sarve, Simperten, Sortal, Sortiva, Tacardia, Tozaar, Xartan, Zaart, Zartan,

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Lopo comes as a tablet to take by mouth. It is usually taken once or twice a day with or without food. To help you remember to take Lopo, take it at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Lopo exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of Lopo and gradually increase your dose.

If your child can not swallow a tablet, talk to your doctor or pharmacist. The pharmacist can prepare a liquid form of this medication for your child.

Lopo controls high blood pressure but does not cure it. Your blood pressure may decrease during the first week of your treatment, but it may take 3 to 6 weeks for you to notice the full benefit of Lopo. Continue to take Lopo even if you feel well. Do not stop taking Lopo without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

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Disseminated forms are those in which two or more noncontiguous sites may be involved. Two other Flavobacteriaceae phylotypes were characteristic of the diatom-dominated microcosms, together with one Alphaproteobacteria phylotype (Roseobacter) and one Gammaproteobacteria phylotype (Methylophaga). Transsection of the rectus abdominis muscle in the treatment of acetabular fractures: operative technique and outcome in 21 patients. The affective structure of supportive parenting: depressive symptoms, immediate emotions, and child-oriented motivation.

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Different depths, lesion volumes and volume concentrations of microspheres are investigated. Blockade of p38alpha MAPK ameliorates acute inflammatory renal injury in rat anti-GBM glomerulonephritis. Bioinformatics studies and polymerase chain reaction (PCR) analyses seem to indicate the absence of ADC-like DNA sequences in the wild-type T.

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Right hemicolectomy combined with pancreatico- duodenectomy for the treatment of colon carcinoma invading the duodenum or pancreas. We have analysed the relationship of blood eosinophil count and serum eosinophil cationic protein (ECP) levels in patients with acute and chronic idiopathic urticaria. Genetic and in vitro studies have shown that Shh also later acts as a midline-derived chemoattractant for commissural axons.

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Endoscopic ultrasonography using a small probe 2.6 mm in diameter at 15 or 20 MHz frequency was employed to determine the depth of superficial esophageal cancer invasion in 54 patients. From these motion estimates, strain images representing the local deformation of the myocardium can be formed to show local myocardial contraction.

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This review summarizes our understanding of lung CSCs and their role in metastasis formation and growth of non- small-cells lung cancer (NSCLC). The development of myelinated nociceptors is dependent upon trks in the trigeminal ganglion.

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The sensory and pain threshold were higher in the obese than in the control subjects. Experimental evidence for the limiting role of enzymatic reactions in chemoattractant-induced pseudopod extension in human neutrophils.

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The beads with the bound complex are deposited on the MALDI sample probe, followed by elution of the retained compounds and removal of the beads. Autopsy found no malformations, and all other bacterial and viral test results were negative. Artificial grammars generated corpora of input strings containing a predetermined and constrained set of sequential statistics. Psychological dimensions of eating behaviour and self-esteem are also of relevance to explore for single mothers and their children.

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There were also other accompanying neuronal migration anomalies and corpus callosum agenesis. Both protocols utilized a dermal sensitization phase with two administrations on days 0 and 7 followed by four inhalation challenges with approximately 38 mg MDI/m(3) in intervals of 2 weeks. To develop a method for determining plasma and renal tissue concentrations of cisplatin (DDP) after subcutaneous DDP implantation in mice.

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Only when stimulated, the naive cells acquire pathogenic capacity and induce ocular inflammation. Ideally, the management of intracranial aneurysms should be based on close collaboration between neurosurgeons and interventional neuroradiologists and the approach (conventional surgery or endovascular) should be discussed case by case.

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Electron microscopy: assays involving freeze-fracture and freeze-etching. We found PpVLG and PpDRH1 expression products in stem cells from stolons and buds of internae, during asexual reproduction of colonial P.

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Postchallenge C-peptide response and hepatic insulin extraction were significantly higher in Caucasians with abdominal obesity. Moreover, the intraoperative intact parathyroid hormone assay (iPTH) now permits to confirm the resection of all hyper-secreting glands. These novel tests will probably combine the information embedded in the expression of multiple genes with mathematical prediction algorithms to formulate classification rules and predict outcome.

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In stage III colon cancer, tumor budding did not provide additional independent prognostic information beyond that given by routine pathology reporting. Mechanistic study on adsorptive removal of tert-butanethiol on Ag-Y zeolite under ambient conditions. Comparison between dopamine transporter affinity and self-administration potency of local anesthetics in rhesus monkeys.

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The present study was designed to evaluate the anti-inflammatory activity of a new parenteral formulation of nimesulide and to correlate it with the pharmacokinetic profile. This study evaluated the reliability of clinical axillary LN assessment by experts and assessed whether inaccuracy can be related to LN size. Intervention patients were less likely to be readmitted to a hospital in general and for the same condition that prompted their index hospitalization at 30, 90, and 180 days versus control patients. This face-directed approach affords high yields without template assistance.

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A prevalent view is that p75(NTR) and TrkA combine to form a high-affinity receptor, but definitive evidence for this is still lacking. In the present study, we found that endoplasmic reticulum (ER) stress induced by a variety of experimental agents stimulated a time- and concentration-dependent increase in HO-1 mRNA and protein in vascular smooth muscle cells (SMC). The interactions between NK cells and dendritic cells (DCs) have been previously demonstrated in vitro. Use and toxicity of complementary and alternative medicines among emergency department patients.

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Despite the improvement of his liver function, the patient died 5 days later due to chronic congestive heart failure. Whereas singlet oxygen caused mainly protein modification reflected by shift of its electrophoretic mobility, action of hydrogen peroxide and superoxide resulted in generation of specific fragments.

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Both baseline non-fasting glucose level and the presence of multiple pre-existing diabetes risk factors appeared to have a major impact on the risk of developing diabetes. Insulin exerts an anti-apoptotic activity by suppressing the excessive accumulation of ROS within cells through signaling pathways including stimulation of PI3 kinase and ERK in HepG2 cells. Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms. Here we report on the identification of peptides targeting the X-inhibitor of apoptosis protein (XIAP). Interhologram cross talk of shift-multiplexed holograms is also modeled using the same method, together with sparse modulation block coding and correlation decoding of data.

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The current study aims to modify the RFFF to utilize a dorsoradial skin island in order to protect the volar tissue aspect of these structures. Another type of approach is to use remifentanil in critically ill patients. Affinity capture and elution/electrospray ionization mass spectrometry assay of phosphomannomutase and phosphomannose isomerase for the multiplex analysis of congenital disorders of glycosylation types Ia and Ib.

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The mechanisms by which anti-galactose alpha 1,3galactose (alpha-Gal) IgG influence NK cell migration across porcine aortic endothelium (PAEC) were investigated. A large amount of the light that is scattered from the retinal layers is recorded by the detector as background, from which it is not trivial to estimate the centroid of the Shack-Hartmann spot.

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However, the association of severity of AKI with the long-term risk of death is not well defined. Furthermore, both the blue-shift and the intensity of the emission saturate with increasing excitation power. DNA methylation may be an important mechanism of inactivation of RUNX3 gene in HCC. Robot-assisted vascular and nodal dissection during video-assisted thoracic surgery lobectomy for early-stage lung cancer is feasible. The muscles were dissected out 24 h later, divided into denervated and innervated halves and then into junctional and extrajunctional regions.

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A feasibility study of 18F-fluorodeoxyglucose positron emission tomography targeting and simultaneous integrated boost for intensity-modulated radiosurgery and radiotherapy. We report a case of a young woman who, following treatment for stage IIIA breast cancer using a high-dose chemotherapy regimen followed by autologous bone marrow and stem cell transplantation, developed respiratory failure and was found to have coronavirus pneumonia as diagnosed by electron microscopy from BAL fluid.

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IgG4-related sclerosing disease should be included in the differential diagnosis of thickening of the pituitary stalk with CDI, and a search for extra-pituitary involvement is essential. We sought to determine how practice patterns for unprotected left main stenosis have changed with the advent of drug-eluting stents (DES). The kinetic properties of RuBP carboxylase/oxygenase were determined in the leaf extracts.

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Effects of age, sex and salivary secretion on the human tongue surface. Finally, histological stainings confirmed that the lack of staining in the external germinal layer of 1-day-old euthyroid chicks was due to the fact that migration of immature granule cells from the external towards the internal layer was completed at this stage while cell migration was retarded in hypothyroid animals. Metabolic syndrome on top of chronic hepatitis B: the more, the worse? We demonstrated by qRT-PCR that PSA-RP2 is upregulated in prostate cancer compared with benign prostatic hyperplasia tissues. Osteoprotegrin and soluble tumor necrosis factor receptor 1 are associated with microalbuminuria in nontreated HIV-infected patients.

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Identification of substrates of the Mycobacterium tuberculosis proteasome. We, therefore, sought to examine the association between HRV and salivary cortisol, which were recorded simultaneously in a stress-exposed, prospective, occupational cohort. For dichotomous outcomes, we considered that an intervention that affected less than one in 10 people would not be clinically worthwhile. The ecological effects on the normal intestinal microflora after cefixime tablets in doses of 200 mg twice daily for 7 days were studied in 10 healthy volunteers.

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The derivatives of SBD-BF with cysteine, cysteinylglycine, homocysteine and glutathione are easily separated by HPLC and their calibration curves show excellent linearity over the range 0.05-20 micromol/L with excellent r(2) values for all analytes. Myocardial lactate, pyruvate, and glucose did not show obvious changes throughout the procedure. In consequence, the binding of a hydrophobic group to a hydrophobic protein cavity is not simply a matter of matching complementary shapes. Persistence of adrenergic response is the main factor leading to the second stage of envenomation, characterized by an increase in resistance to venous return (Rv) and a decrease in CO.

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A longevity study through repeated cycle experiments was conducted to analyze the effect of activity loss on the reaction mechanistic pathway, and the results showed that the attenuation in the nanoparticles activity did not adversely affect the reaction mechanisms in generating gaseous products such as ethylene and ethane. The study was designed to observe the effects of long-term treatment with candesartan cilexetil (candesartan) on blood pressure (BP), blood pressure variability (BPV), baroreflex sensitivity (BRS) and end-organ damage (EOD) in sinoaortic denervated (SAD) rats. On the other hand, the oxidation temperature did not show a significant effect on the deposit in the range examined.

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Therapy with statins reduces lipid levels but may also have other beneficial (eg, antiinflammatory) effects. This implies that the changes in EL were due mostly to increased heterogeneity of regional ventilation, and that non-dependent lung regions may remain virtually unaffected mechanically even when the overall oedematous changes in lung mechanics are severe. Prevalence and risk factors of habitual snoring in primary school children. In vivo Matrigel plug assay for angiogenesis, the inclusion of 1 nM apelin in the Matrigel resulted in clear capillary-like formations with an increase of hemoglobin content in the plug. Quetiapine should be considered with partial response or if EPS develop, and clozapine is an option with treatment-refractory patients.

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Ethylacetate and the mixture of acetone-methanol (1:1) exhibited better extraction efficiencies. A curvature-mediated mechanism for localization of lipids to bacterial poles.

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Immunocytochemistry revealed a toxin-induced reduction in lamina I, of SPR and of NMDA NR1 subunit receptor expressing neurons, and of c-Fos, an inducible molecular marker of persistent nociceptive activity. In order to model how these measured kinetics values for polymerase gamma affect the final function of the polymerase, the replication of an entire strand of mitochondrial DNA, we implement a stochastic simulation of the series of reaction events that the polymerase carries out.

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Differential permeability of blood microvasculatures in various sympathetic ganglia of rodents. The sinus was gently debrided with a curette and then filled with fibrin glue. Initial experiments with proteinase mutants and proteinase inhibitors showed reduction of histological damage. Microscanning enables both qualitative and quantitative analysis of the bone microarchitecture.

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Following our previous demonstration that sulforaphane induces cell cycle arrest and apoptosis in human T lymphoblastoid Jurkat leukemia cells and increases p53 and bax protein expression, we tested sulforaphane on non-transformed phytohemagglutinin-stimulated human lymphocytes. This has prompted the recent development of non-myeloablative conditioning regimens for allogeneic HCT that have opened the way to include elderly patients and those with comorbid conditions. Association of calcium-phosphorus product with blood pressure in dialysis. Genotypes of the renin-angiotensin system have been implicated in essential hypertension and in progression of native kidney diseases, but gene effects on progression in chronic renal allograft dysfunction are unclear.

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The chemiluminescence from the singlet oxygen was emitted in the course of the collapse of the interface under laminar flow condition. Nine internationally recognised scoring systems were used to calculate severity of injury, in order to predict the chances of patient survival. However, an association between the elevated enzyme concentration and drug treatment could not be clearly established. Laboratory Exercises with Outlines for the Study of (Chemistry, to accompany any Elementary Text.

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We here identified a short segment of HBHA whose presence is mandatory for the stability of folded conformation, whose denaturation is a reversible two-state process. After 48 h, only arachidonic acid and conjugated linoleic acid (CLA) enhanced GSH content through an induction of gamma-glutamylcysteine ligase. Such knowledge has also informed improved definition of mild traumatic brain injury, and allowed validation of management guidelines.

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Delayed cerebral vasospasm after aneurysmal subarachnoid hemorrhage causes cerebral ischemia and infarction. Further follow-up will show if this treatment is effective in preventing negative remodeling of the left ventricle and reveal potential late adverse events (arrhythmogenicity and propensity for restenosis). Randomized controlled trials comparing vaccines against Plasmodium falciparum, P.

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Three-dimensional (3D) spheroids are a good model for studying in vitro chemosensitivity because they reproduce unicellular and multicellular mechanisms of drug resistance. The survivorship of the different types of revisions was estimated using the Kaplan-Meier method and compared using proportional hazard models. At 8 and 22 weeks of age, animals of both groups were subjected to the plus maze test to assess their anxiety levels. Tissue analyses confirmed that in adrenal gland, kidney, liver and lung, alpha-tocopherol concentrations were higher following D-alpha than DL-alpha-tocopherol supplementation. These results helped to identify other potential factors regulating folate synthesis, suggesting ways to further enhance folate levels in food crops.

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Study of bacterial adhesion to prosthetic valve materials in vitro Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation. Accurate molecular detection of melanoma nodal metastases: an assessment of multimarker assay specificity, sensitivity, and detection rate.

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Induced cell fusion after the accumulation of certain substances in the surface membrane. In contrast to split-brain or alexithymic people, expressive-creative persons verbalized their presentational symbolization and imagery of the right hemisphere which was transformed via corpus callosum to the left hemisphere, called symbollexia. In the derivatization and extraction procedure, 2,4-dinitrophenylhydrazine (DNPH) as derivatization reagent and formic acid as catalyzer were injected into the sample solution for derivatization with aldehydes, then the formed hydrazones was rapidly extracted by dispersive liquid-liquid microextraction with 1-dodecanol as extraction solvent.

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As a result, hepatocytes and fibroblasts adhered only to the LPAN(3) and PMMA lane, respectively. We conclude that both AR and ER beta are important in relatively early coronary atherosclerosis, but inversely so, because decreasing AR and increasing ER beta expression correlate hasil pemilukada lotim ntb coupons with more extensive atherosclerosis. Importantly, the adult human duct cells retain their capacity to recapitulate ngn3-induced embryonic (neuro)endocrine differentiation after proliferation.

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To assess the impact of furozenol 40 mg of prozac being an only child on characteristics of parental and peer relationships, school achievement, social and sexual behavior. Inhibition of protein kinase C promotes neuronal survival in low potassium through an Akt-dependent pathway.

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Deamination of 5mC to thymine proceeds via formation of the intermediate photohydrate. The incidence of complications of chronic otitis media augmentin dose aspiration pneumonia and cholesteatoma has decreased since the proliferation of antibiotics early in the twentieth century. Alpha-2 adrenergic receptors stimulate actin organization in developing fetal rat cardiac myocytes. Intramedullary and extramedullary solitary fibrous tumor of the cervical spine.

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PTEN-associated tumor syndromes should be considered in the differential diagnosis of C-cell hyperplasia of the thyroid. The lack of bell's palsy treatment acyclovir dose for cold basic organizational and decision-making skills needed to provide positive nurturing can interfere with the health and development of their children.

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Debulking or biopsy of malignant glioma in elderly people - a randomised study. Both 99mTc BN and 111In asec india address finder O scans provided normal findings in the two subjects affected by benign adenoma, while 111In O was positive in only two of three patients with cancer and was always unable to detect nodal invasion. We present a case which illustrates some of the complexities of perioperative management. Intraosseous vascular anomalies are rare, and although they have been described in the facial skeleton, those occurring in the zygomatic bone are extremely rare. Overall, engaging the patient to observe routine behaviors may lead to the identification of modifiable activities, which might be aggravating or manifesting as a playing-related discomfort.

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Two patients in early fifties also achieved good results and hence this procedure should be offered to this age group also. The complex regulatory and biosynthetic pathways involved in cell wall biosynthesis and construction offer useful chemotherapeutic targets against mycobacteria. The mental status was assessed by means of the Mini-Mental State Examination (MMSE) and the 15-item cardizem la vs cardizem sr 120 Geriatric Depression Scale (GDS). Miconazole oral gel enhances acenocoumarol anticoagulant activity: a report of three cases. This study aimed to map the sentinel nodes of gastric carcinoma and to estimate the clinical usefulness of sentinel node biopsy.

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MAb P3134 raised to strain NT24 reacted with OspA and the OspB-ranging protein of these isolates and cross-reacted with the OspB-ranging protein of some other isolates. In immunocompromised patients with altered cell mediated immunity, and rarely in healthy individuals, varicella results in a life-threatening infection. Lower urogenital tract anatomical and functional phenotype in lysyl oxidase like-1 knockout mice resembles female pelvic floor dysfunction in humans. Mammalian AGTRL1 has been shown to modulate cardiac contractility, venous and arterial dilation, and endothelial cell migration in vitro, but fenofibrato 250 mg manipulado no role in the development of the vasculature, or other tissues, has been described.

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Recent studies have elucidated various mechanisms in this resistance, such as induction of drug efflux pumps, in particular certain of the ABC transporters. Four dose di augmentin sciroppo men and eight women, aged 31-82 years old, with XGC were reviewed. The purpose of this study was to determine which COX isoform, COX-1 or COX-2, is responsible for regulating the protective surface pH gradient and to test if COX inhibitors also had non-COX mediated effects in vivo. Advanced practice nurses are particularly suited for working with adolescents because of their holistic approach to client care.

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This observational cohort study examines effects of preoperative use of renin-angiotensin system (RAS) inhibitors on postoperative renal marcelo sarvas married with children failure in aging patients undergoing cardiac surgery. For such cases, a multidisciplinary treatment is crucial to improve the prognosis of the disease.

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