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Losaprex (Losartan)
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Losartan

Factors involved in the effects of Losaprex on endothelial dysfunction induced by aging in SHR. We have used the nonpeptide angiotensin II (ANG II) receptor antagonists Losaprex (receptor subtype AT1) and PD-123319 (AT2) to determine the participation of ANG II receptor subtypes in luteinizing hormone-releasing hormone (LHRH)-induced prolactin release in a perifusion study using intact pituitaries in vitro.

Other names for this medication:
Losartan, Cozaar, Lortaan, Losacar, Losakind, Lostat, Omnitan, Losium, Angilock, Angizaar, Aratan, Araten, Cardon, Cartan, Cormac, Corodin, Corus, Cosart, Covance, Eklips, Etan, Fensartan, Fortzaar, Hilos, Lacine, Lara, Larb, Lavestra, Lifezar, Loben, Logika, Loortan, Lopo, Lorista, Losa, Losacor, Losan, Losap, Losaprex, Losar, Losart, Losartanum, Losartas, Losatan, Losatrix, Lostan, Lotan, Lotar, Lotim, Lozap, Lozar, Lyosan, Mozartan, Niten, Normatens, Ocsaar, Osartil, Ostan, Prelow, Prosan, Rasertan, Rasoltan, Repace, Resilo, Rosatan, Sarilen, Sarlo, Sarvas, Sarve, Simperten, Sortal, Sortiva, Tacardia, Tozaar, Xartan, Zaart, Zartan,

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Losaprex is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of strokes and heart attacks.

Losaprex is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, Losaprex relaxes the blood vessels. A lower blood pressure will increase the supply of the blood and oxygen to the heart.

Losaprex is also used to decrease the risk of stroke in patients with high blood pressure and enlargement of the heart. It is also used to treat kidney problems in patients with type 2 diabetes and a history of hypertension.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

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Treatment of torture survivors - influences of the exile situation on the course of the traumatic process amd therapeutic possibilities. This present study includes four additional years and now covers about 1.9 million individual birth certificates. DITPA stimulates arteriolar growth and modifies myocardial postinfarction remodeling.

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Recent epidemiological studies have measured these consequences in terms of excess mortality associated with resistance, increased duration of illness, and increased risk of invasive illness or hospitalization following infections with resistant Salmonella. Septal plugs associated with developmental processes or aging hyphae typically occur by the accumulation of sealing material. During the past 4 years, from January 1991 to December 1994, we experienced 12 cases of aortic root reconstruction utilizing Carrel patch method. Two new species of Yorkeria (Tetraphyllidea: Onchobothriidae) from Chiloscyllium punctatum (Elasmobranchii: Hemiscylliidae) in Thailand. Neurologic examination revealed motor loss and hyperesthesia to touch, vibration, pressure, and temperature from her groin to toes in the left leg only.

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Under pentobarbital anesthesia, mice were fixed to a stereotaxic apparatus, and electrodes were implanted into the frontal and occipital cortex. T(3)-induced osteocalcin synthesis was significantly reduced by SB203580 or PD169316 also in primary cultured mouse osteoblasts. Bronchoconstriction occurs in athletes during prolonged exercise and may thus influence performance. In etsrp morphants, which are deficient in endothelial and HSC development, scl-alpha alone partially rescues angioblast specification, arterial-venous differentiation, and the expression of HSC markers, runx1 and c-myb, whereas scl-beta requires angioblast rescue by fli1a to restore runx1 expression.

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We subsequently found that dtl/cdt2 is required for normal cell cycle control, primarily to prevent rereplication. We also describe how observational and instructed fear is distinguished by involvement of additional neural systems implicated in social-emotional behavior, language and explicit memory, and propose a modified conditioning model to account for social fear learning. Aortic cannulation and proximal anastomosis of the planned vein graft were impossible. International guidelines have been developed to guide medical management according to asthma severity defined by lung function and symptom frequency.

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We discuss the pathological and clinical aspects of this disease and review the literature. When making technology system selections or upgrades, nurse executives are expected to negotiate with vendors as well as the CIO and department directors. In contrast, PNAR is a condition with similar symptomatology but in which the patient has no identifiable specific allergic sensitivities. The EC(50) values obtained after exposure of the catfish primary hepatocytes for 72h to MC-LR, winter and summer extracts was about 0.091, 0.053 and 0.014 mg/l, respectively. Endoscopy and biopsy of the duodenum were performed for immunoglobulin A endomysial antibody-positive patients and pathologic evaluation was done according to modified Marsh classification.

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One problem that precludes comparison of most published studies is that they use either relative risk, or absolute risk, or sensitivity and specificity. Many of the rocks dredged are variously decomposed and hydrated, but there is no evidence of important chemical modification toward conversion of the lava flows to spilite during extrusion or solidification. Policy statements adopted by the Governing Council of the American Public Health Association, November 18, 1998.

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Thus, melatonin and linoleic acid represent two important environmental signals that interact in a unique manner to regulate tumor progression and ultimately the host-cancer balance. Over a period of 20 years (1978 - 1998) 1280 children were operated on, 368 bilaterally, which resulted in 1648 antireflux ureterocystoneostomies being performed.

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More generally, our results indicate that by combining ecological and molecular genetic data, it is possible to understand the forces acting on life history transitions at the level of specific loci. Our data suggest that LFA-1-mediated homotypic cell-cell adhesion is involved in myeloma cell proliferation and raises the possibility that this interaction may have a crucial role in in vivo myeloma cell growth. Evaluations of health interventions in social insurance-based countries: Germany, the Netherlands, and Austria. Pentostatin and rituximab therapy for previously untreated patients with B-cell chronic lymphocytic leukemia. Hence, our findings show that the induction of cancer cell death before the injection of oncolytic HSV enhances intratumoral virus delivery/penetration and antitumor efficacy.

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It was confirmed that after coating thiolated Eudragit, the percentage of TECMs remained on the isolated porcine intestinal mucosa surface was significantly higher than those of CMs and ECMs. The method is simple, since it is primarily based on classical Fresnel imaging.

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Burden of illness score for elderly persons: risk adjustment incorporating the cumulative impact of diseases, physiologic abnormalities, and functional impairments. The objective of this study was to examine the chemistry of trace elements in CBM product water at discharge points and in associated holding ponds across the Powder River Basin, Wyoming.

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In addition, our data indicate that either N-terminal or CCIIZ domain disruption may cause hNinein conformational change which recruits gamma-tubulin to centrosomal or noncentrosomal hNinein-containing sites, implying that the gamma-tubulin localization may be hNinein-dependent. Patient safety must never be compromised and pharmacological sedation must be administered by a trained practitioner, with appropriate patient monitoring and provision of supplementary oxygen. Surveyor V landed in a small crater, 8.5 meters wide and 12.5 meters long, which was probably formed by drainage of surficial fragmental debris into a subsurface fissure.

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A larger cohort, with long-term follow-up, is necessary to validate our results. Renal oncocytomatosis in a long-term hemodialysis patient is extremely rare. The content of vitamin E, endoperoxide-derived malonaldehyde, lipofluorescent material and polyunsaturated fatty acids, and the activities of catalase, glutathione reductase, and glutathione peroxidase were then measured in cerebral tissues, with or without intoxication with methyl ethyl ketone peroxide (MEKP).

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Total middle ear reconstructive surgery is suitable for patients with chronic otorrhea complicating radical mastoidectomy. Surprisingly, the analyses indicate that retention was not impaired when similar motions of the two objects required retrieval of incompatible torque responses, but retention was impaired when similar patterns of motion in the two tasks required similar patterns of applied torque. The serine hydrolases and cysteine proteases have provided the proofs of concept for activity-based proteomics, and other studies are rapidly following. Semi-thin, 0.5-micron sections of each were cut and viewed at 20,000 x magnification. Deficits in hippocampal and anterior cingulate functioning during verbal declarative memory encoding in midlife major depression.

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Finally, addressing N-glycosylation from an archaeal perspective is providing new general insight into this event, as exemplified by the solution of the first crystal structure of an oligosaccharide transferase from an archaeal source. Sinusitis is overdiagnosed as a cause of headache because of the belief that pain over the sinuses must be related to the sinuses. In man, the latter is formed by angiotensin-converting enzyme or chimase.

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The phenomenon in Brazil seems numerically stable for the age group from 15 to 19 years old, with a trend of increase in the first segment of adolescence, below 15. The functional significance of the morphological results and the interactions of Sertoli and germ cells during spermatogenesis are discussed.

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To test the hypothesis that circulating androgens regulate RBD-1 mRNA expression in the epididymis, rats were subjected to bilateral orchiectomy (orch) or to orch plus a 3.5-cm implant containing testosterone. A prospective study in 52 patients revealed surprisingly high rates of intravascular fluid loads without clinical manifestations. For the case of (18)F-FDG, a dose was given with no information about placental transfer of the radiopharmaceutical.

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Wide contoured thigh cuffs and automated limb occlusion measurement allow lower tourniquet pressures. The present study documents activation of calpain-1 throughout brain white matter in aged animals, evidenced by immunodetection of the activated enzyme as well as a calpain-derived spectrin fragment in both tissue section and Triton X-100-soluble homogenate of subcortical white matter from the frontal, temporal, and parietal lobes. In this study we investigated the involvement of the EGFR and intracellular signal transduction pathways in the PV-IgG-induced apoptosis.

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Bileaflet mechanical prostheses for aortic valve replacement in patients younger than 65 years and 65 years of age or older: major thromboembolic and hemorrhagic complications. Our increasing awareness of the pathologic roles of iron, as well as of the methods for prevention of iron loading coupled with intensified research and development of tissue specific iron chelator drugs, can be expected to yield marked improvements in human health. Some countries have not shown significant increases in potency, while other countries have not monitored potency over time. These findings suggest that NKA, SP and CGRP could act as neurotransmitters at the first central synapses of the trigeminal nociceptive pathway to transmit the sensory stimuli to the higher brain centers.

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However, this L-arginine-derived autacoid may have a role in the irritant-induced CGRP release from afferent vasodilator fibres in the skin. It accepts as input a circular dichroism spectrum and outputs the estimated secondary structure content (alpha-helix and beta-strand) of the corresponding protein, as well as an estimated measure of error. Transfectants expressing hLHR-872/1847 demonstrated greatly reduced ligand binding and ligand-induced cAMP accumulation in comparison to those expressing wild type hLHR. Experiments on hydraulic jumps in turbidity currents near a canyon-fan transition. In contrast, there was mainly increased mRNA expression of Growth Arrest and DNA Damage-inducible gene 153 (GADD153), which seemed to be at the level of transcription rather than mRNA stability.

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Cryopreservation and autografting of ovarian tissue may preserve fertility after cancer treatment, but could be hampered by tumour cell contamination. New treatment options for erectile dysfunction in patients with diabetes mellitus. Hydrolysis of sophorose, laminaribiose, and gentiobiose were also rather slow, and hydrolysis of cellobiose was even slower.

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Leptin responsiveness to energy restriction: genetic variation in the leptin receptor gene. A unique PDZ ligand in PKCalpha confers induction of cerebellar long-term synaptic depression. It is very necessary to undertake daily physical activity for primary prevention of osteoporosis in both males and females. Using in succession chest X-rays, CT-densitometry and fine-needle aspiration biopsy, a conservative approach can be advised in specific cases.

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We identified all hospitalizations in small rural hospitals (less than 50 beds) in New York State from 1998 to 2001 that included an ICD-9 procedure code for 1 of 9 procedures for which there is a documented volume-outcomes association: abdominal aortic aneurysm repair, aortic-valve replacement, carotid endarterectomy, colectomy, coronary artery bypass, cystectomy, esophagectomy, pancreatectomy, or pulmonary resection. In this paper, an analysis of uncertainty was performed to estimate the uncertainty of model predictions and to screen out crucial variables using a Monte Carlo stochastic approach and a number of statistical methods, including ANOVA and stepwise multiple regression. The inclusion of pIE1 upstream of pIE2 (pIE1IE2) enhanced progestin but not glucocorticoid responsiveness.

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In summary, increased seed sink strength for N in AAP-12 stimulates seed growth, but also that of vegetative organs, which finally leads to a higher ratio of vegetative to seed biomass at maturity and thus a lower harvest index. Patients received ondansetron 4 mg or metoclopramide 10 mg intravenously in a double-blind manner at the end of anaesthesia. The data dictionary is provided to different medical research networks by means of the software tool Onto-Builder via the internet.

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The present results suggest that megakaryocytes contribute to random selection of an excess of neutrophils in the bone marrow of rats treated with LPS. Consensus among physiotherapists in the united kingdom on the use of normal saline instillation prior to endotracheal suction: a Delphi study. The sensitivities of 3 tumor cell lines (C6, SRS-82 and LoVo) to nolaterex were determined by growth inhibition test. Pleomorphic lobular carcinoma of the breast is a high nuclear grade variant of lobular carcinoma. The RNFL and the layer including the ganglion cell layer are significantly thinner in patients with ADOA associated with an OPA1 gene mutation, whereas the photoreceptor layers are not affected morphologically.

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Thus, unlike certain vertebrate transferrin lineages, no widespread evidence for pathogen-mediated positive selection was detected at this locus. To compare the effects of splinting alone in the treatment of ulnar nerve lesion at the elbow with the effects of applying a local steroid injection in addition to splinting. This was a sample of patients from a localized region of the United States.

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Molecular subtyping and genetic analysis of the enterohemolysin gene (ehxA) from Shiga toxin-producing escherichia coli and atypical enteropathogenic E. Thus, HV-BBI is a potent inhibitor of trypsin and the lysyl (K) residue that occupies the P1 position appears to be optimal for potency of action against this protease. Among skin cancers, melanoma is probably the most highly invasive and metastasizing, with a poor outcome. Modulation of serum parathyroid hormone and ionized calcium concentrations during reproduction in rats fed a low calcium diet.

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The cause of pigment epithelial tears at the edge of a pigment epithelial detachment (PED) following transpupillary thermotherapy in eyes with associated age-related macular degeneration is unclear. Distribution of obestatin and ghrelin in human tissues: immunoreactive cells in the gastrointestinal tract, pancreas, and mammary glands. Lastly, a review of esophagopulmonary fistulas will also be provided. Pharmacological modulation of the KATPs within the BG alters GABAergic activity and produces behavioural changes.

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The advantage of our design is that the actual feedback mechanism depends only on a single gene and does not require any other modulation. Entrainer effect on photochirogenesis in near- and supercritical carbon dioxide: dramatic enhancement of enantioselectivity. The DA complex, however, stimulates assembly of the enhanceosome itself such that the entire reaction can occur in a highly concerted manner.

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Electrodermal activity in relation to cortisol dysregulation in depressive patients. Multidetector aldactazide dose neonatal blood pressure CT angiography in the follow-up of patients treated with renal artery stents: value of different reformation techniques compared with axial source images. This is the second of two papers in which we study a mathematical model of cytoskeleton-induced neuron death. Testis morphology showed that, during early infancy, the 5-alpha-reductase enzyme deficiency may not have affected interstitial or tubular development.

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Mobile Decision Support for Advanced Practice Nurses (MODS-APN) is a PDA-based decision support tool designed to assist APNs in the diagnosis and management of smoking cessation, obesity, topiramate side effects in women hair loss and depression. The aim of this study was to report the initial experience with a novel catheter in the retrograde approach for chronic total occlusion (CTO). However, ultrasonography has other advantages in the assessment of pelvic organ prolapse, most notably in the differential diagnosis of posterior compartment prolapse, which can be due to at least 5 different conditions. The cDNA clones were of 2055 and 1941 base pairs in length, and contained a 2018-bp complete open reading frame (ORF) and a 1785-bp partial coding sequence, respectively.

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