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Losartan

This effect was inhibited by the selective angiotensin II type 1 receptor antagonist Prelow. The acute effects of the angiotensin II receptor antagonist Prelow on uric acid and oxypurine metabolism were evaluated. Effects of central Prelow on plasma renin and centrally mediated natriuresis.

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Somewhat unexpectedly, a constitutively (PRL-independent) mutant form of the PRL-R was obtained after deletion of the S2 subdomain. We report an extremely unusual case of an ascending aortic dissecting aneurysm associated with an isolated medial intramural hematoma in the right pulmonary artery in an 86-year-old woman with clinical manifestations mimicking pulmonary embolism.

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Production of free radical species in cells and body tissues is known to cause many pathological disorders. Design of a nursing clinical decision support system applying nursing diagnosis and nursing evaluation model based data mining. The correlation among fragment ions in a tandem mass spectrum is crucial in reducing stochastic mismatches for peptide identification by database searching. Arterial or venous thromboembolism is rarely encountered clinically as an extradigestive tract complication in inflammatory bowel disease (IBD).

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The INK4A/ARF locus on chromosome 9 is one of the sites mutated most frequently in human cancer. RNAi-mediated silencing of TEL/AML1 reveals a heat-shock protein- and survivin-dependent mechanism for survival. Microvascular decompression is safe and effective method in the treatment of trigeminal neuralgia.

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In vitro studies suggest that macrophage glucocerebroside storage leads to tissue dysfunction through complex mechanisms involving altered intracellular calcium homeostasis and apoptosis. The overall level of neuroticism is moderately higher and extraversion somewhat lower in BD patients than in the general population. In summary, our results indicate that Se plays an important role as an anti-inflammatory agent by tightly regulating the expression of pro-inflammatory genes in immune cells.

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An R package of our tests can be downloaded from the supplementary website http://www.somnathdatta.org/Supp/DNA. Diagnostic value of quantitative sensory testing (QST) in carpal tunnel syndrome. Long-range interlayer interactions in ferroelectric liquid crystals.

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While genome-wide hypomethylation renders chromosomes instable, hypermethylation of CpGs in promoter regions is generally associated with transcriptional silencing, e.g., of tumor suppressor genes. Ab initio calculations show that (5,5) and (6,6) single-walled gallium nitride nanotubes (GaN NTs) in bundles could aggregate spontaneously to form new condensed phases when bundled tubes are close enough under hydrostatic pressure. Two weeks prior to the experiment, diabetes was induced by a single intravenous injection of streptozotocin (55 mg/kg BW). Assessment of postural instability in patients with traumatic brain injury upon enrolment in a vocational adjustment programme. None of the other mutants exhibited significant inhibition of platelet aggregation.

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On comparing least-squares and MM-estimation, MM-estimation was superior to least-squares estimation in that parameter estimates were more efficient and outliers were clearly identified. A case-control study of consecutive patients with RA, matched for age, sex and duration of disease, attending the same clinics. Putative amino acid sequences of CA10-3, AS16-1 and CA17-1 showed high homologies with known genes related to intracellular signaling, transcription and aerobic metabolism. For polymerase delta, the Km values were 2.0 microM for dGTP and 3.5 microM for dTTP.

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Recent progress shed light on various factors, including adiponectin, MIF, H11K, and metformin in the activation of AMPK. In the stage of matrix formation, the organic matrix of the collar enameloid contains a number of collagen fibers, and odontoblasts display features suggesting that these cells actively synthesized and secreted collagen.

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Unintentional overdoses, alcohol abuse, and underlying liver disease might increase the risk of hepatotoxicity. Clinical experience with endoscopic stents for treatment of common bile duct stones. There is little information on the incidence of autoimmune hepatitis (AIH) because on many occasions the disease can progress asymptomatically, different diagnostic criteria have been proposed during the last 20 years, and many epidemiological studies are based on retrospective clinical series.

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It is concluded that all women should be assured of access to highly effective contraceptive methods. Although it is generally felt that working in the healthcare sector is clean and without risk, healthcare staff and especially physicians and nurses who generally work very long hours are actually exposed to various occupational risks. The biochemical changes seen after CO(2) laser resurfacing proceed through a well-organized and highly reproducible wound healing response that results in marked alterations in dermal structure. A macrosocial version of the Matthew principle is apparently involved in those processes of social selection that currently lead to the concentration of scientific resources and talent (50). Meteorological satellites have provided the first complete data on energy exchange between earth and space.

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These studies indicate that the Dspp-Cre transgenic mice will be valuable to generate odontoblast-specific gene knockout mice so as to gain insight into the molecular roles of critical genes in the odontoblasts during dentinogenesis. Perhaps in postmenopausal women other factors than oestrogen and progesterone levels, could influence vaginal polymicrobic flora.

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