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Esperal (Disulfiram)

Esperal was the first medication approved by the U.S. Food and Drug Administration (FDA) to treat chronic alcohol dependence. In its pure state, Esperal is a white to off-white, odorless, almost tasteless powder, which is soluble in water and alcohol. Esperal, an alcohol-aversive or alcohol-sensitizing agent, causes an acutely toxic physical reaction when mixed with alcohol. Continuing research and clinical findings have clarified Esperal's mode of action and established its safe and effective use in the treatment of alcohol use disorders (AUDs) in some patient groups.

Other names for this medication:
Disulfiram, Antabuse, Anticol, Aversan, Esperal, Etabus, Tenutex,

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Esperal is used to help overcome your drinking problem. It is not a cure for alcoholism, but rather will discourage you from drinking.

Esperal is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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How conceptual frameworks influence clinical practice: Evidence from the writings of John Thelwall, a 19th-century speech therapist. We have investigated the molecular mechanisms by which selective Toll-like receptor (TLR)2 and TLR4 agonists regulate expression of CCR1 and CCR2 on primary human monocytes and THP-1 cells, a human monocytic cell line.

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A total of 663 patients with chronic heart failure who underwent cardiopulmonary exercise testing were tracked for cardiac mortality and HTx. The relationship of birth weight with cardiovascular risk factors, namely, systolic and diastolic blood pressure (BP), BMI, HDL, LDL, triglycerides, and HOMA insulin resistance (HOMA-IR) was examined retrospectively using information on 1155 participants (730 whites and 425 African-Americans) from two cohorts of the Bogalusa Heart Study.

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The imperative to establish so-called endophenotypes-quantifiable measures of risk for neurological dysfunction-is a growing focus of research in schizophrenia. Fluorescent dyes typically are readily soluble in alcohol, xylene, and other common solvents used for conventional paraffin processing.

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